铜稳态：晚期分泌途径的特殊功能。
Copper homeostasis: specialized functions of the late secretory pathway.
机构信息
Marine Biological Laboratory, Woods Hole, MA 02543, USA.
出版信息
Dev Cell. 2014 Jun 23;29(6):631-2. doi: 10.1016/j.devcel.2014.06.002.
PMID:24960690
Abstract
Differentiated cells have evolved mechanisms to adapt the functions of the late secretory pathway to the specific needs of the organism. Reporting in this issue of Developmental Cell, Polishchuk et al. (2014) demonstrate that hepatocytes utilize a unique exocytic aspect of the late endosomal/lysosomal compartment to maintain organismal copper homeostasis.
摘要
分化细胞已经进化出了适应晚期分泌途径功能的机制，以满足生物体的特殊需求。在本期《发育细胞》中，波兰丘克等人（2014）证明了肝细胞利用晚期内体/溶酶体隔室的独特胞吐作用来维持生物体的铜稳态。
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