Kataria K, Yadav R, Seenu V
All India Institute of Medical Sciences, New Delhi, India.
J Surg Case Rep. 2012 Feb 1;2012(2):5. doi: 10.1093/jscr/2012.2.5.
Primary gallbladder carcinoma is a malignant neoplasm with an incidence of 1.2 cases per 100 000 people each year. Its occurrence increases with age, particularly in women. It is the fifth most common cancer of the gastrointestinal tract, and the most common malignancy in the biliary tract. Adenocarcinoma is the most common type of gallbladder neoplasm whereas sarcomatoid carcinoma is rare with an incidence of less than one percent of all malignant gall bladder neoplasms. Sarcomatoid carcinomas are composed of malignant epithelial and sarcomatous components, sometimes with heterologous sarcomatous elements. In general, conservative treatments are thought to be unfavourable to the tumor. Prognosis is poor following curative resection for carcinosarcoma of the gall bladder because of recurrence as systemic metastasis of the liver and peritoneal dissemination.
原发性胆囊癌是一种恶性肿瘤，每年发病率为每10万人中有1.2例。其发病率随年龄增长而增加，在女性中尤为明显。它是胃肠道第五大常见癌症，也是胆道最常见的恶性肿瘤。腺癌是胆囊肿瘤最常见的类型，而肉瘤样癌罕见，发病率不到所有恶性胆囊肿瘤的1%。肉瘤样癌由恶性上皮和肉瘤成分组成，有时还伴有异源性肉瘤成分。一般认为，保守治疗对该肿瘤不利。胆囊癌肉瘤根治性切除术后预后较差，因为会复发，出现肝脏全身转移和腹膜播散。
