Lata Jeevan, Ahmad Fahad, Chand Vimal
Department of Oral and Maxillofacial Surgery, Punjab Government Dental College and Hospital, Punjab, India.
Department of Pathology, Amritsar, Punjab, India.
Contemp Clin Dent. 2014 Apr;5(2):247-51. doi: 10.4103/0976-237X.132372.
Myoepithelial carcinoma is a rare neoplasm of salivary glands that account for < 1% of all salivary gland tumors. The most common sites of involvement are major salivary glands mainly parotid gland. Intraorally, it can arise from minor salivary glands; palate is the most common site of occurrence. It also occurs in nasopharynx, paranasal sinuses, nasal cavity and larynx in head and neck region. Myoepithelial tumors were first described in 1943. Their malignant variant, myoepithelial carcinoma, was first reported by Stromeyer et al., in 1975, characterized by distinct morphologic heterogeneity and an infiltrative growth pattern into adjacent tissues. Here, we report a rare case of a 55-year-old female with myoepithelial carcinoma of buccal mucosa. It was also rare because of unusual location of tumor. Our patient was treated with wide local resection and remained free of disease for 15 months.
肌上皮癌是一种罕见的唾液腺肿瘤,占所有唾液腺肿瘤的比例不到1%。最常受累的部位是主要的唾液腺,主要是腮腺。在口腔内,它可起源于小唾液腺;腭部是最常见的发生部位。它也发生于头颈部区域的鼻咽、鼻窦、鼻腔和喉部。肌上皮肿瘤于1943年首次被描述。其恶性变体——肌上皮癌,于1975年由斯特罗迈尔等人首次报道,其特征是形态学上具有明显的异质性以及向相邻组织浸润性生长的模式。在此,我们报告一例罕见的55岁女性颊黏膜肌上皮癌病例。该病例还因肿瘤位置不寻常而罕见。我们的患者接受了广泛局部切除治疗,并且在15个月内无疾病复发。