Chikly Amanda, Durst Ronen, Lotan Chaim, Chen Shmuel
Department of Internal Medicine, Hebrew University, Hadassah Ein Kerem Medical Center, P.O. Box 12000, 91120 Jerusalem, Israel.
Department of Cardiology, Hebrew University, Hadassah Ein Kerem Medical Center, P.O. Box 12000, 91120 Jerusalem, Israel.
Case Rep Cardiol. 2014;2014:964038. doi: 10.1155/2014/964038. Epub 2014 May 22.
Myocarditis consists of an inflammation of the cardiac muscle, definitively diagnosed by endomyocardial biopsy. The causal agents are primarily infectious: in developed countries, viruses appear to be the main cause, whereas in developing countries rheumatic carditis, Chagas disease, and HIV are frequent causes. Furthermore, myocarditis can be indirectly induced by an infectious agent and occurs following a latency period during which antibodies are created. Typically, myocarditis observed in rheumatic fever related to group A streptococcal (GAS) infection occurs after 2- to 3-week period of latency. In other instances, myocarditis can occur within few days following a streptococcal infection; thus, it does not fit the criteria for rheumatic fever. Myocarditis classically presents as acute heart failure, and can also be manifested by tachyarrhythmia or chest pain. Likewise, GAS-related myocarditis reportedly mimics myocardial infarction (MI) with typical chest pain, electrocardiograph changes, and troponin elevation. Here we describe a case of recurrent myocarditis, 5 years apart, with clinical presentation imitating an acute MI in an otherwise healthy 37-year-old man. Both episodes occurred 3 days after GAS pharyngitis and resolved quickly following medical treatment.
心肌炎是指心肌的炎症,通过心内膜心肌活检可明确诊断。其病因主要为感染性:在发达国家,病毒似乎是主要病因,而在发展中国家,风湿性心脏病、恰加斯病和艾滋病是常见病因。此外,心肌炎可由感染因子间接诱发,并在产生抗体的潜伏期后发生。通常,与A组链球菌(GAS)感染相关的风湿热中观察到的心肌炎在潜伏期2至3周后出现。在其他情况下,心肌炎可在链球菌感染后几天内发生;因此,它不符合风湿热的标准。心肌炎典型表现为急性心力衰竭,也可表现为快速性心律失常或胸痛。同样,据报道,与GAS相关的心肌炎会出现典型胸痛、心电图改变和肌钙蛋白升高,类似心肌梗死(MI)。在此,我们描述一例复发性心肌炎病例,间隔5年,临床表现为一名37岁健康男性疑似急性心肌梗死。两次发作均发生在GAS咽炎后3天,经治疗后迅速缓解。