Barr James Geoffrey, Jane Clayton Elizabeth Sarah, Sotheran Wendy
Breast Surgery Department, St Richard's Hospital, Chichester, UK
Breast Surgery Department, St Richard's Hospital, Chichester, UK.
J Surg Case Rep. 2013 Feb 7;2013(2):rjs047. doi: 10.1093/jscr/rjs047.
Metaplastic breast cancers (MPBCs) represent <1% of breast cancers. Reports of MPBC in men are limited to case reports. We report a case of MPBC with pulmonary metastasis occurring in a 59-year-old man who initially presented with a presumed breast abscess. Histology from the breast lesion revealed a poorly differentiated carcinoma and a computed tomography scan showed an ulcerative right-sided breast mass and an area of scarring in the apex of the left lung. The breast lesion and the lung lesion were resected separately and the histology from the lung showed a poorly differentiated carcinoma with sarcomatous features in keeping with metastasis from a primary breast cancer. Our patient then proceeded to chemotherapy with FEC 100 regimen (5-fluorouracil, epirubicin and cyclophosphamide). MPBC is an aggressive breast cancer that has a propensity to metastasis to the lungs. Prognosis is poor.
化生性乳腺癌（MPBC）占乳腺癌的比例不到1%。关于男性MPBC的报道仅限于病例报告。我们报告一例发生肺转移的MPBC病例，患者为一名59岁男性，最初表现为疑似乳腺脓肿。乳腺病变的组织学检查显示为低分化癌，计算机断层扫描显示右侧乳腺有溃疡性肿块，左肺尖有瘢痕形成区域。乳腺病变和肺部病变分别进行了切除，肺部组织学检查显示为低分化癌，具有肉瘤样特征，符合原发性乳腺癌转移。随后，我们的患者接受了FEC 100方案（5-氟尿嘧啶、表柔比星和环磷酰胺）化疗。MPBC是一种侵袭性乳腺癌，容易转移至肺部。预后较差。
