Allergy & Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK.
Department of Psychology, School of Life and Health Sciences, Aston University, Birmingham, UK.
NPJ Prim Care Respir Med. 2014 Jun 26;24:14020. doi: 10.1038/npjpcrm.2014.20.
Patient-reported outcome measures (PROMs) are measures of the outcome of treatment(s) reported directly by the patient or carer. There is increasing international policy interest in using these to assess the impact of clinical care.
To identify suitably validated PROMs for asthma and examine their potential for use in clinical settings.
We systematically searched MEDLINE, EMBASE and Web of Science databases from 1990 onwards to identify PROMs for asthma. These were critically appraised, then narratively synthesised. We also identified the generic PROMs commonly used alongside asthma-specific PROMs.
We identified 68 PROMs for asthma, 13 of which were selected through screening as being adequately developed to warrant full-quality appraisal: 8 for adults, 4 for children and 1 for a child's caregiver. The PROMs found to be sufficiently well validated to offer promise for use in clinical settings were the Asthma Quality of Life Questionnaire (AQLQ) and mini-AQLQ for adults, and Pediatric Asthma Quality of Life Questionnaire for children. Rhinasthma was considered promising in simultaneously assessing the impact of asthma and rhinitis in those with coexistent disease. We identified 28 generic PROMs commonly used in conjunction with asthma-specific instruments.
We identified asthma PROMs that offer the greatest potential for use in clinical settings. Further work is needed to assess whether these are fit-for-purpose for use in clinical practice with individual patients. In particular, there is a need to ensure these are validated for use in clinical settings, acceptable to patients, caregivers and clinicians, and yield meaningful outcomes.
患者报告的结局测量（PROMs）是指患者或护理人员直接报告的治疗结果的测量。越来越多的国际政策对使用这些方法来评估临床护理的影响感兴趣。
确定适合哮喘的验证后的 PROMs，并研究它们在临床环境中的应用潜力。
我们系统地检索了 1990 年以来的 MEDLINE、EMBASE 和 Web of Science 数据库，以确定哮喘的 PROMs。对这些 PROMs 进行了严格的评价，然后进行了叙述性综合。我们还确定了与哮喘特定 PROMs 一起使用的通用 PROMs。
我们确定了 68 种哮喘 PROMs，其中 13 种通过筛选被认为是充分发展的，可以进行全面质量评估：8 种用于成人，4 种用于儿童，1 种用于儿童的护理人员。经过充分验证，有望在临床环境中使用的 PROMs 是成人的哮喘生活质量问卷（AQLQ）和迷你 AQLQ，以及儿童的儿科哮喘生活质量问卷。Rhinasthma 被认为在同时评估同时患有哮喘和鼻炎的患者的疾病影响方面具有潜力。我们确定了 28 种通用 PROMs，通常与哮喘特定仪器一起使用。
我们确定了最有潜力在临床环境中使用的哮喘 PROMs。需要进一步研究这些 PROMs 是否适合在临床实践中与个体患者一起使用。特别是需要确保这些 PROMs 在临床环境中得到验证，被患者、护理人员和临床医生接受，并产生有意义的结果。
