Department of Pediatrics, Division of Child and Adolescent Health, Columbia University College of Physicians and Surgeons, 622 West 168th St, PH 17th Fl. Room 102A, New York, NY 10032, USA.
Expert Rev Vaccines. 2014 Aug;13(8):1013-26. doi: 10.1586/14760584.2014.933076. Epub 2014 Jun 26.
HPV infection leads to significant morbidity and mortality worldwide. The HPV vaccine is currently licensed and recommended for adolescents and young adults in many countries. Nonetheless, coverage levels remain low, especially in settings using a clinic-based rather than school-based delivery model. Health care professionals (HCPs) have the potential to strongly impact HPV vaccine acceptability and uptake, yet often fail to discuss and/or strongly recommend HPV vaccination. This article reviews the myriad factors that influence HPV vaccination, focusing, in particular, on those relevant to HCP communication with patients and families. It also provides a historical framework and highlights recent evidence related to HPV vaccination that may be valuable for these conversations. Lastly, it discusses strategies targeting HCPs and their practices that may increase HPV vaccination initiation and completion rates globally.
HPV 感染在全球范围内导致了大量的发病率和死亡率。目前，许多国家都批准并推荐青少年和年轻人接种 HPV 疫苗。然而，覆盖率仍然很低，特别是在采用基于诊所而不是基于学校的接种模式的环境中。医疗保健专业人员（HCPs）有可能对 HPV 疫苗的可接受性和接种率产生重大影响，但他们往往未能讨论和/或强烈推荐 HPV 疫苗接种。本文回顾了影响 HPV 疫苗接种的众多因素，特别关注与 HCP 与患者和家属沟通相关的因素。它还提供了一个历史框架，并强调了与 HPV 疫苗接种相关的最新证据，这些证据可能对这些对话有价值。最后，它讨论了针对 HCPs 及其实践的策略，这些策略可能会提高全球 HPV 疫苗接种的起始和完成率。
