Jeon In Kyung, Park Chul Jong, Lee Mu-Hyoung, Lee Dong Youn, Kang Hee Young, Hann Seung Kyung, Choi Gwang Seong, Lee Hee Jung, Kim Tae Heung, Lee Ai-Young, Oh Sang Ho
Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Department of Dermatology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea.
Ann Dermatol. 2014 Jun;26(3):349-56. doi: 10.5021/ad.2014.26.3.349. Epub 2014 Jun 12.
It was previously thought that persons with genetic predispositions to vitiligo develop the condition after exposure to various precipitating environmental factors. However, in many cases, the aggravating factors of vitiligo have not been clearly identified.
To identify the aggravating factors of vitiligo in the working environment and daily life.
A total of 489 vitiligo patients were recruited from 10 institutions in South Korea; patients were provided with a questionnaire about environmental factors and behavior patterns in the workplace and in daily life, and their association with vitiligo.
Ninety-five of the 470 enrolled patients (20.2%) answered that environmental risk factors in daily life and in the workplace affected the development of vitiligo. The most frequently attributed causes were trauma and burn (13.6%), followed by sunlight (12.8%), stress (12.8%), cleaning products/disinfectant/chemicals (4.9%), and hair dye (2.1%).
Vitiligo of the hand and foot was associated with frequent exposure to aggravating materials and overexposure to sunlight, along with frequent trauma of these areas, all of which could be considered important risk factors of vitiligo. The development of vitiligo could potentially be controlled through the early detection of aggravating factors.
以前认为,具有白癜风遗传易感性的人在接触各种诱发环境因素后会患上该病。然而,在许多情况下,白癜风的加重因素尚未明确。
确定工作环境和日常生活中白癜风的加重因素。
从韩国10家机构招募了489名白癜风患者;向患者提供了一份关于工作场所和日常生活中的环境因素及行为模式及其与白癜风关联的问卷。
470名登记患者中有95名(20.2%)回答说,日常生活和工作场所中的环境危险因素会影响白癜风的发展。最常提及的原因是创伤和烧伤(13.6%),其次是阳光(12.8%)、压力(12.8%)、清洁产品/消毒剂/化学品(4.9%)和染发剂(2.1%)。
手足白癜风与频繁接触加重物质、过度暴露于阳光下以及这些部位的频繁创伤有关,所有这些都可被视为白癜风的重要危险因素。通过早期发现加重因素,有可能控制白癜风的发展。