Lee Young-Bok, Kim Hei-Sung
Department of Dermatology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, Seoul 06591, Korea.
Department of Dermatology, Incheon St. Mary's Hospital, The Catholic University of Korea, Seoul 06591, Korea.
J Clin Med. 2021 Aug 31;10(17):3958. doi: 10.3390/jcm10173958.
Adult height is linked to the risk of several diseases, but its association with vitiligo has not been established. This study aimed to investigate the relationship between adult height and vitiligo incidence. Korean nationwide claims data from 15,980,754 individuals (20 years of age or older) who received a health checkup during the period 2005-2008, were examined. Subjects were categorized into age- and gender-specific height quintiles. Participants were followed until vitiligo diagnosis or until the end of 2015. The Cox proportional-hazards model for cumulative risk was computed for height categories. During the follow-up period, 29,196 cases (136,020,214 person-years) of newly diagnosed vitiligo were reported. A positive association was found between height and risk of vitiligo in which the hazard ratio between the highest and lowest quintiles of height was 1.36 (95% confidence interval: 1.31-1.42). While more diverse cohort studies are needed, our findings suggest that taller stature increases the risk of vitiligo.
成人身高与多种疾病的风险相关，但它与白癜风的关联尚未明确。本研究旨在调查成人身高与白癜风发病率之间的关系。研究人员检查了2005年至2008年期间接受健康检查的15,980,754名20岁及以上韩国人的全国索赔数据。受试者按年龄和性别分为身高五分位数组。对参与者进行随访，直至诊断出白癜风或直至2015年底。计算了身高类别累积风险的Cox比例风险模型。在随访期间，报告了29,196例新诊断的白癜风病例（136,020,214人年）。发现身高与白癜风风险之间存在正相关，其中身高最高和最低五分位数之间的风险比为1.36（95%置信区间：1.31-1.42）。虽然需要更多样化的队列研究，但我们的研究结果表明，较高的身材会增加患白癜风的风险。
