Seo Bommie F, Jung Hyun Wook, Choi Ik Kyun, Rhie Jong Won
Department of Plastic and Reconstructive Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Ann Dermatol. 2014 Jun;26(3):395-8. doi: 10.5021/ad.2014.26.3.395. Epub 2014 Jun 12.
Sebaceous carcinoma is a very rare and potentially aggressive carcinoma originating from the epithelial lining of the sebaceous gland. More than 70% of all cases are in the head and neck region, especially the periorbita; therefore, they are classified into ocular and extraocular sebaceous carcinoma. The reported risk factors are advanced age, male sex, previous irradiation, and genetic predisposition for Muir-Torre syndrome. The current case is of sebaceous carcinoma found in the suprapubic area of a 67-year-old male patient who had received liver transplantation 6 years before, and had been receiving oral tacrolimus. Examination of the gastrointestinal system did not reveal any other malignancies. Although nonmelanoma skin cancers may occur as a complication after liver transplantation, there have been no previous reports of sebaceous carcinoma after liver transplantation. Furthermore, the sebaceous carcinoma in this case occurred in an uncommon location. We report this case along with a review of the literature.
皮脂腺癌是一种非常罕见且具有潜在侵袭性的癌，起源于皮脂腺的上皮内衬。所有病例中超过70%位于头颈部区域，尤其是眶周；因此，它们被分为眼内和眼外皮脂腺癌。报道的危险因素包括高龄、男性、既往放疗以及穆尔-托里综合征的遗传易感性。本例为一名67岁男性患者，6年前接受肝移植，一直在口服他克莫司，在耻骨上区发现皮脂腺癌。胃肠道系统检查未发现任何其他恶性肿瘤。虽然非黑色素瘤皮肤癌可能作为肝移植后的并发症出现，但此前尚无肝移植后发生皮脂腺癌的报道。此外，本例皮脂腺癌发生在一个不常见的部位。我们报告该病例并对文献进行综述。
