Cakan Derya Germec, Ulkur Feyza, Taner Tulin
Department of Orthodontics, Faculty of Dentistry, Yeditepe University, Istanbul, Turkiye.
Department of Orthodontics, Faculty of Dentistry, Hacettepe University, Ankara, Turkiye.
Eur J Dent. 2013 Sep;7(Suppl 1):S143-S147. doi: 10.4103/1305-7456.119092.
The interruption of odontogenesis by any etiological factor may result in dental anomalies. Apart from the environmental factors, the impact of genetics in dental anomalies was found to be a factor in different levels. Many authors had questioned a common genetic defect resulting in different phenotypic conditions such as absent, malformed, malposed or ectopic teeth. Because the multidisciplinary treatment of these dental anomalies such as hypodontia, impaction etc., involves orthodontic intervention, orthodontists must be aware of the etiology and possible correlative conditions with dental anomalies.
任何病因导致的牙胚发育中断都可能引发牙齿异常。除环境因素外，遗传学在牙齿异常中的影响在不同层面均被发现是一个因素。许多作者质疑是否存在一种共同的基因缺陷导致诸如牙齿缺失、形态异常、位置异常或异位等不同的表型状况。由于这些牙齿异常（如牙量不足、阻生等）的多学科治疗涉及正畸干预，正畸医生必须了解牙齿异常的病因及可能的相关情况。
