Sahu N, Patnaik B K
Department of Zoology, D.A.V. College, Titilagarh, India.
Arch Gerontol Geriatr. 1989 Jan;8(1):55-62. doi: 10.1016/0167-4943(89)90070-8.
Administration of T4 (1 microgram/g body-weight on alternate days) to male garden lizards of three different age groups (young, middle-aged and old) for a period of 2 weeks caused a significant rise in the hepatic oxygen consumption, the degree of response increasing with advancing age. On the other hand, when treated in vitro (5 micrograms T4 in the medium) the stimulation of hepatic oxygen consumption was observed only in lizards of the young age group. Oral administration of thiourea (0.05 mg/g body-weight on alternate days, three doses) led to a decrease in hepatic oxygen uptake, the degree of inhibition being higher in young (30%) and old (28%) than in middle-aged lizards (12%).
对三个不同年龄组（幼年、中年和老年）的雄性园蜥每隔一天给予甲状腺素（1微克/克体重），持续2周，会导致肝脏耗氧量显著增加，反应程度随年龄增长而增强。另一方面，当在体外进行处理（培养基中加入5微克甲状腺素）时，仅在幼年组的蜥蜴中观察到肝脏耗氧量的刺激作用。口服硫脲（每隔一天0.05毫克/克体重，共三剂）会导致肝脏摄氧量减少，幼年（30%）和老年（28%）蜥蜴的抑制程度高于中年蜥蜴（12%）。
