Sas-Korczyńska Beata, Mituś Jerzy, Stelmach Andrzej, Ryś Janusz, Majczyk Anna
Clinic of Oncology - Department of Breast and Chest Cancer, Centre of Oncology - Maria Sklodowska-Curie Memorial Institute, Krakow Branch, Poland.
Department of Oncological Surgery, Centre of Oncology - Maria Sklodowska-Curie Memorial Institute, Krakow Branch, Poland.
Contemp Oncol (Pozn). 2014;18(2):120-3. doi: 10.5114/wo.2014.42727. Epub 2014 Jun 3.
To present the characteristics and clinical outcomes in 94 patients with mucinous breast cancer treated at the Oncology Centre in Krakow between 1952 and 2002.
Stage I or II carcinomas were found in 66 patients (69.4%) of the presented group and in the remaining 28 patients (29.8%) stage III disease was diagnosed. In 27 cases regional lymph nodes were involved. All patients had been treated with surgery: mastectomy (90 patients) or breast-conserving treatment (4 patients). Radiotherapy was administered in 14 patients, adjuvant chemo-therapy in 14 patients, and endocrine therapy in 39 patients.
The maximum follow-up was 257 months. Ten-year survival was as follows: 75.7% (overall survival), 82.5% (disease-free survival). During the follow-up, 4 patients developed local recurrence, 5 patients developed metastases. Second primary cancer was found in 8 patients.
The presented results confirm the good prognosis in patients treated for mucinous breast cancer. The diagnosis of early-stage breast cancer based on mammography can allow breast-conserving treatment.
介绍1952年至2002年期间在克拉科夫肿瘤中心接受治疗的94例黏液性乳腺癌患者的特征及临床结果。
该组66例患者(69.4%)为Ⅰ期或Ⅱ期癌,其余28例患者(29.8%)诊断为Ⅲ期疾病。27例有区域淋巴结受累。所有患者均接受了手术治疗:乳房切除术(90例)或保乳治疗(4例)。14例患者接受了放疗,14例患者接受了辅助化疗,39例患者接受了内分泌治疗。
最长随访时间为257个月。10年生存率如下:总生存率75.7%,无病生存率82.5%。随访期间,4例患者出现局部复发,5例患者出现转移。8例患者发现第二原发性癌症。
所呈现的结果证实黏液性乳腺癌患者预后良好。基于乳腺X线摄影的早期乳腺癌诊断可允许进行保乳治疗。