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黏液性乳腺癌——1952年至2002年间在克拉科夫肿瘤中心接受治疗的患者的临床特征及治疗结果

Mucinous breast cancer - clinical characteristics and treatment results in patients treated at the Oncology Centre in Kraków between 1952 and 2002.

作者信息

Sas-Korczyńska Beata, Mituś Jerzy, Stelmach Andrzej, Ryś Janusz, Majczyk Anna

机构信息

Clinic of Oncology - Department of Breast and Chest Cancer, Centre of Oncology - Maria Sklodowska-Curie Memorial Institute, Krakow Branch, Poland.

Department of Oncological Surgery, Centre of Oncology - Maria Sklodowska-Curie Memorial Institute, Krakow Branch, Poland.

出版信息

Contemp Oncol (Pozn). 2014;18(2):120-3. doi: 10.5114/wo.2014.42727. Epub 2014 Jun 3.

DOI:10.5114/wo.2014.42727
PMID:24966796
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4068815/
Abstract

AIM OF THE STUDY

To present the characteristics and clinical outcomes in 94 patients with mucinous breast cancer treated at the Oncology Centre in Krakow between 1952 and 2002.

MATERIAL AND METHODS

Stage I or II carcinomas were found in 66 patients (69.4%) of the presented group and in the remaining 28 patients (29.8%) stage III disease was diagnosed. In 27 cases regional lymph nodes were involved. All patients had been treated with surgery: mastectomy (90 patients) or breast-conserving treatment (4 patients). Radiotherapy was administered in 14 patients, adjuvant chemo-therapy in 14 patients, and endocrine therapy in 39 patients.

RESULTS

The maximum follow-up was 257 months. Ten-year survival was as follows: 75.7% (overall survival), 82.5% (disease-free survival). During the follow-up, 4 patients developed local recurrence, 5 patients developed metastases. Second primary cancer was found in 8 patients.

CONCLUSIONS

The presented results confirm the good prognosis in patients treated for mucinous breast cancer. The diagnosis of early-stage breast cancer based on mammography can allow breast-conserving treatment.

摘要

研究目的

介绍1952年至2002年期间在克拉科夫肿瘤中心接受治疗的94例黏液性乳腺癌患者的特征及临床结果。

材料与方法

该组66例患者(69.4%)为Ⅰ期或Ⅱ期癌,其余28例患者(29.8%)诊断为Ⅲ期疾病。27例有区域淋巴结受累。所有患者均接受了手术治疗:乳房切除术(90例)或保乳治疗(4例)。14例患者接受了放疗,14例患者接受了辅助化疗,39例患者接受了内分泌治疗。

结果

最长随访时间为257个月。10年生存率如下:总生存率75.7%,无病生存率82.5%。随访期间,4例患者出现局部复发,5例患者出现转移。8例患者发现第二原发性癌症。

结论

所呈现的结果证实黏液性乳腺癌患者预后良好。基于乳腺X线摄影的早期乳腺癌诊断可允许进行保乳治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fee/4068815/383d0d091ba8/WO-18-22754-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fee/4068815/383d0d091ba8/WO-18-22754-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fee/4068815/383d0d091ba8/WO-18-22754-g001.jpg

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本文引用的文献

1
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J Med Imaging Radiat Oncol. 2013 Feb;57(1):25-31. doi: 10.1111/1754-9485.12006. Epub 2012 Dec 28.
2
Pure and mixed mucinous carcinoma of the breast: fine needle aspiration cytology findings and review of the literature.乳腺单纯性和混合性黏液癌:细针穿刺细胞学检查结果及文献复习
Cytopathology. 2013 Dec;24(6):377-84. doi: 10.1111/cyt.12016. Epub 2012 Sep 21.
3
Risk factors for uncommon histologic subtypes of breast cancer using centralized pathology review in the Breast Cancer Family Registry.
罕见乳腺癌组织学类型——一项回顾性研究及文献综述
J Clin Med. 2024 Jan 23;13(3):643. doi: 10.3390/jcm13030643.
4
HER2-positive pure mucinous breast carcinoma: A case report and literature review.人表皮生长因子受体2阳性纯黏液性乳腺癌:一例报告及文献复习
Medicine (Baltimore). 2020 Aug 14;99(33):e20996. doi: 10.1097/MD.0000000000020996.
5
Omission of adjuvant radiotherapy following breast-conserving surgery for elderly women with early-stage pure mucinous breast carcinoma.保乳手术后老年早期纯黏液性乳腺癌患者省略辅助放疗。
Radiat Oncol. 2019 Nov 4;14(1):190. doi: 10.1186/s13014-019-1394-x.
6
Invasive Colloid Carcinoma and the role of Ki-67 and HER2 - Two case reports.浸润性黏液癌以及Ki-67和HER2的作用——两例病例报告
Radiol Case Rep. 2018 Dec 13;14(3):337-342. doi: 10.1016/j.radcr.2018.11.005. eCollection 2019 Mar.
7
Pure mucinous breast carcinoma in a 25-year-old female, a case report.一名25岁女性的纯黏液性乳腺癌病例报告。
Int J Surg Case Rep. 2018;53:58-60. doi: 10.1016/j.ijscr.2018.10.009. Epub 2018 Oct 17.
8
Clinicopathological Characteristics of Mucinous Breast Cancer: A Retrospective Analysis of a 10-Year Study.黏液性乳腺癌的临床病理特征:一项为期10年研究的回顾性分析
PLoS One. 2016 May 27;11(5):e0155132. doi: 10.1371/journal.pone.0155132. eCollection 2016.
利用乳腺癌家族登记处的集中病理审查,研究乳腺癌少见组织学亚型的危险因素。
Breast Cancer Res Treat. 2012 Aug;134(3):1209-20. doi: 10.1007/s10549-012-2056-y. Epub 2012 Apr 25.
4
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5
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J Breast Cancer. 2011 Dec;14(4):308-13. doi: 10.4048/jbc.2011.14.4.308. Epub 2011 Dec 27.
6
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Arch Pathol Lab Med. 2011 Dec;135(12):1533-8. doi: 10.5858/arpa.2010-0652-CP.
7
Unusual malignant breast lesions: imaging-pathological correlations.罕见恶性乳腺病变:影像学-病理学相关性。
Diagn Interv Radiol. 2012 May-Jun;18(3):270-6. doi: 10.4261/1305-3825.DIR.4454-11.2. Epub 2011 Sep 17.
8
Risk of mortality by histologic type of breast cancer in the United States.美国乳腺癌组织学分型的死亡率风险。
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9
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Breast Care (Basel). 2008;3(3):190-196. doi: 10.1159/000136826. Epub 2008 Jun 19.
10
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Am J Surg. 2008 Oct;196(4):549-51. doi: 10.1016/j.amjsurg.2008.06.013.