Barkley Christina R, Ligibel Jennifer A, Wong Julia S, Lipsitz Stuart, Smith Barbara L, Golshan Mehra
Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Am J Surg. 2008 Oct;196(4):549-51. doi: 10.1016/j.amjsurg.2008.06.013.
Mucinous breast cancer is typically associated with a favorable prognosis. This study aimed to assess recent trends and prognostic features in the treatment of mucinous breast carcinoma.
A retrospective review of our database of patients who presented with mucinous breast cancer was performed. We evaluated patient and tumor characteristics and examined the relationships between these factors and risk for locoregional recurrence.
One hundred eleven patients with mucinous breast cancer were identified. Seventy-one (64%) underwent lumpectomy with radiotherapy. Fourteen (13%) had lymph node metastasis, and node positivity was associated with larger tumor size; node-positive patients had a mean tumor size of 2.7 cm compared with 1.5 cm for node-negative patients (P = .0003). No patients with tumor size <1 cm had lymph node metastasis. Five patients (5%) had local and/or distant recurrence.
Mucinous breast cancer is associated with a low recurrence rate as well as a low incidence of lymph node metastasis. In patients with small (<1 cm) tumors, consideration for deferring nodal evaluation may be made.
黏液性乳腺癌通常预后良好。本研究旨在评估黏液性乳腺癌治疗的近期趋势和预后特征。
对我们数据库中黏液性乳腺癌患者进行回顾性分析。我们评估了患者和肿瘤特征，并研究了这些因素与局部区域复发风险之间的关系。
共识别出111例黏液性乳腺癌患者。71例（64%）接受了保乳手术加放疗。14例（13%）有淋巴结转移，淋巴结阳性与肿瘤较大有关；淋巴结阳性患者的平均肿瘤大小为2.7 cm，而淋巴结阴性患者为1.5 cm（P = .0003）。肿瘤大小<1 cm的患者均无淋巴结转移。5例（5%）出现局部和/或远处复发。
黏液性乳腺癌复发率低，淋巴结转移发生率也低。对于肿瘤较小（<1 cm）的患者，可考虑推迟淋巴结评估。
