Aoyagi Teiichiro, Tachibana Masaaki, Naganuma Shinji
Department of Urology, Tokyo Medical University Ibaraki Medical Center, 3-20-1 Chuo Ami, Ibaraki, Inashiki 300-0395, Japan.
Department of Urology, Tokyo Medical University, Tokyo, Japan.
ISRN Nephrol. 2013 May 22;2013:521949. doi: 10.5402/2013/521949. eCollection 2013.
We here present the results of ultrasonographic (US) evaluations on the alteration of renal diameter of chronic HD patients. Of 109 outpatient HD patients who had neither severe acquired cystic disease of the kidney nor hereditary polycystic kidney disease, we performed US two or three times to measure their maximum renal diameter (mean of both kidneys), and the yearly alteration rate was calculated. The average interval of the two measurements was 35.9 months, and the average HD duration from the HD induction to the first measurement was 29.5 months. The average decrease rate of renal diameter was 4.34 ± 0.4 (SE) mm/year. No statistical difference was seen on the decrease rate in relation to gender, age and original disease (among three groups, glomerulonephritis and IgA nephropathy, diabetes, and others including hypertension). However, the decrease rate was large when the first measurement was close to the induction of hemodialysis, suggesting that the alteration rate reduced according to the hemodialysis vintage (5.3 ± 0.8 mm/year, first measurement not more than 10 months after induction of HD and 1.5 ± 1.6 mm/year, first measurement more than 80 months after induction of HD). Renal diameter decreased approximately 4.3 mm each year, and the decrease rate slowed as the length of time on dialysis increased.
我们在此展示了对慢性血液透析（HD）患者肾直径变化的超声（US）评估结果。在109例既没有严重获得性肾囊肿病也没有遗传性多囊肾疾病的门诊HD患者中，我们进行了两到三次超声检查以测量其最大肾直径（双肾平均值），并计算年变化率。两次测量的平均间隔为35.9个月，从开始HD到首次测量的平均HD时长为29.5个月。肾直径的平均减小率为4.34±0.4（SE）mm/年。在减小率方面，未观察到与性别、年龄和原发病（三组：肾小球肾炎和IgA肾病、糖尿病以及包括高血压在内的其他疾病）相关的统计学差异。然而，当首次测量接近血液透析开始时，减小率较大，这表明变化率会随着血液透析龄期而降低（HD开始后不超过10个月进行首次测量时为5.3±0.8mm/年，HD开始后超过80个月进行首次测量时为1.5±1.6mm/年）。肾直径每年大约减小4.3mm，且随着透析时间的延长，减小率减缓。
