Wittkowski K M
Dept Computer Science, University of Pittsburgh, PA 15260.
AIDS. 1989 Mar;3(3):143-5.
It has been recently advocated that avoiding partners who may be at high risk of carrying HIV provides 5000-fold better protection against HIV infection than usage of condoms [1]. In this paper, it is demonstrated that this guideline is largely based on unrealistic assumptions. If the sensitivity of identifying high-risk partners, realistic estimates of the efficiency of mechanical and chemical barrier methods, and the compliance in following either strategy are taken into account, use of condoms and/or suppositories containing nonoxynol-9 might be more effective than the attempt to avoid high-risk partners. Thus, both barrier methods should be strongly recommended for casual sexual heterosexual contacts.
最近有人主张，避免与可能携带艾滋病毒风险较高的性伴侣接触，比使用安全套预防艾滋病毒感染的效果要好5000倍[1]。本文表明，该指导方针在很大程度上基于不切实际的假设。如果考虑到识别高风险伴侣的敏感性、对机械和化学屏障方法有效性的实际估计以及遵循任何一种策略的依从性，那么使用安全套和/或含有壬苯醇醚-9的栓剂可能比试图避免与高风险伴侣接触更有效。因此，对于随意的异性性接触，强烈推荐使用这两种屏障方法。
