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pH 依赖性生物合成银纳米颗粒对临床病原体的抗菌活性

Antibacterial activity of pH-dependent biosynthesized silver nanoparticles against clinical pathogen.

作者信息

Chitra Kethirabalan, Annadurai Gurusamy

机构信息

Environmental Nanotechnology Division, Sri Paramakalyani Centre for Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, Tamilnadu 627412, India.

出版信息

Biomed Res Int. 2014;2014:725165. doi: 10.1155/2014/725165. Epub 2014 May 21.

DOI:10.1155/2014/725165
PMID:24967396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4054877/
Abstract

Simple, nontoxic, environmental friendly method is employed for the production of silver nanoparticles. In this study the synthesized nanoparticles UV absorption band occurred at 400 nm because of the surface Plasmon resonance of silver nanoparticles. The pH of the medium plays important role in the synthesis of control shaped and sized nanoparticles. The colour intensity of the aqueous solution varied with pH. In this study, at pH 9, the colour of the aqueous solution was dark brown, whereas in pH 5 the colour was yellowish brown; the colour difference in the aqueous solution occurred due to the higher production of silver nanoparticles. The antibacterial activity of biosynthesized silver nanoparticles was carried out against E. coli. The silver nanoparticles synthesized at pH 9 showed maximum antibacterial activity at 50 μL.

摘要

采用简单、无毒、环保的方法制备银纳米颗粒。在本研究中,由于银纳米颗粒的表面等离子体共振,合成的纳米颗粒的紫外吸收带出现在400nm处。介质的pH值在控制纳米颗粒的形状和尺寸合成中起着重要作用。水溶液的颜色强度随pH值而变化。在本研究中,在pH 9时,水溶液的颜色为深棕色,而在pH 5时,颜色为黄褐色;水溶液中的颜色差异是由于银纳米颗粒产量较高所致。对生物合成的银纳米颗粒针对大肠杆菌进行了抗菌活性测试。在pH 9合成的银纳米颗粒在50μL时显示出最大抗菌活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/79d15087cf30/BMRI2014-725165.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/a2e0f5675a3b/BMRI2014-725165.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/c5d6ac520a11/BMRI2014-725165.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/b226cacd8076/BMRI2014-725165.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/6cafce9db9b6/BMRI2014-725165.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/2845ad53c1e9/BMRI2014-725165.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/79d15087cf30/BMRI2014-725165.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/a2e0f5675a3b/BMRI2014-725165.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/c5d6ac520a11/BMRI2014-725165.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/b226cacd8076/BMRI2014-725165.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/6cafce9db9b6/BMRI2014-725165.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/2845ad53c1e9/BMRI2014-725165.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de67/4054877/79d15087cf30/BMRI2014-725165.006.jpg

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