Suppr超能文献

[一名城市地区女孩被诊断为播散性幼年型副球孢子菌病]

[Disseminated juvenile paracoccidioidomycosis diagnosed in a girl in an urban area].

作者信息

Ballesteros Angélica, Beltrán Sandra, Patiño Jaime, Bernal Cynthia, Orduz Rocío

机构信息

Departamento de Pediatría, Clínica Universitaria Colombia, Bogotá, D.C, Colombia.

出版信息

Biomedica. 2014 Jan-Mar;34(1):21-8. doi: 10.1590/S0120-41572014000100005.

Abstract

INTRODUCTION

Paracoccidioidomycosis is one of the most prevalent systemic fungal infections in Latin American countries. The incidence rate has been increasing and its detection has gotten increasingly common in travelers or immigrants from endemic areas. It is characterized by respiratory symptoms, lymphadenopathies and skin lesions, which gradually progress and subsequently lead to death in some untreated chronic disease cases.

OBJECTIVE

To describe the clinical approach and diagnosis of an exotic tropical pathology in an urban area.

CASE DESCRIPTION

Case description and extended literature review. We made a case report of urban paracoccidioidomycosis in a young patient, with a clinical syndrome of fever for a month, widespread nodal involvement, cutaneous manifestations and weight loss. During the physical examination, hepatosplenomegaly and a febrile episode were evidenced, whose diagnosis was difficult. Management started with itraconazole and trimethoprim sulfamethoxazole, with subsequent cessation of spiking fevers and significant improvement of the skin lesions. We performed a comprehensive literature review, with search criteria performed in PubMed and adapted for different databases. The review was conducted based on the studies found in Medline, LILACS, SciELO and Cochrane Library, from 1966 up to this moment. Studies were selected by the authors based on their relevance and scientific contribution to the discussion of this case.

CONCLUSIONS

There are few cases of paracoccidiomycosis in the pediatric population despite the endemicity of this entity in Latin America. An increasing population influx from endemic areas makes suspecting of this disease a must.

摘要

引言

副球孢子菌病是拉丁美洲国家最常见的系统性真菌感染之一。其发病率一直在上升,在来自流行地区的旅行者或移民中,其检出率也越来越高。它的特征是呼吸道症状、淋巴结病和皮肤病变,这些症状会逐渐发展,在一些未经治疗的慢性病病例中最终导致死亡。

目的

描述城市地区一种外来热带疾病的临床处理方法和诊断。

病例描述

病例描述及广泛的文献综述。我们报告了一名年轻患者的城市副球孢子菌病病例,该患者有长达一个月的发热临床综合征、广泛的淋巴结受累、皮肤表现和体重减轻。体格检查发现肝脾肿大和发热,诊断困难。治疗从伊曲康唑和复方新诺明开始,随后高热停止,皮肤病变明显改善。我们进行了全面的文献综述,搜索标准在PubMed中执行,并适用于不同数据库。该综述基于1966年至今在Medline、LILACS、SciELO和Cochrane图书馆中找到的研究进行。作者根据研究与该病例讨论的相关性和科学贡献来选择研究。

结论

尽管副球孢子菌病在拉丁美洲具有地方性,但儿科患者中的病例很少。来自流行地区的人口流入增加,使得怀疑这种疾病成为必要。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验