Ortíz Guillermo, Dueñas Carmelo, Rodríguez Ferney, Barrera Lena, de La Rosa Gisela, Dennis Rodolfo, Granados Marcela, Londoño Darío, Molina Francisco, Jaimes Fabián
Departamento de Cuidado Intensivo, Hospital Santa Clara, Bogotá, D.C, Colombia.
Departamento de Cuidado Intensivo, Hospital Bocagrande, Cartagena, Colombia.
Biomedica. 2014 Jan-Mar;34(1):40-7. doi: 10.1590/S0120-41572014000100007.
Currently, there is not enough data available concerning sepsis in developing countries, especially in Latin America.
We developed a study aimed at determining the frequency, clinical and epidemiological characteristics, and the consequences of sepsis in patients requiring admission to intensive care units in Colombia.
This was a secondary analysis of a prospective cohort study carried out over a six-month period, from September 1, 2007, to February 28, 2008, in ten medical/surgical intensive care units in four Colombian cities. Patients were considered eligible if they had a probable or confirmed diagnosis of infection according to medical records. We recorded demographic characteristics, first admission diagnosis and co-morbidities, clinical status, and sepsis, severe sepsis or septic shock.
During the study period, 826 patients were admitted to the intensive care units. From these patients, 421 (51%) developed sepsis in the community, 361 (44%) in the ICU, and 44 (5%) during hospitalization in the general ward. Two hundred and fifty three patients (30.6%) had involvement of one organ system: 20% had respiratory involvement, followed by kidney and central nervous system involvement with 3.4% and 2.7%, respectively.
In our cohort of septic patients, the prevalence of sepsis treated in ICU is similar to that reported in other studies, as well as the overall mortality.
目前，关于发展中国家的败血症，尤其是拉丁美洲的相关数据不足。
我们开展了一项研究，旨在确定哥伦比亚需要入住重症监护病房的患者中败血症的发生率、临床和流行病学特征以及后果。
这是对一项前瞻性队列研究的二次分析，该研究于2007年9月1日至2008年2月28日在哥伦比亚四个城市的十个内科/外科重症监护病房进行，为期六个月。根据病历记录，若患者有疑似或确诊感染，则被视为符合条件。我们记录了人口统计学特征、首次入院诊断和合并症、临床状况以及败血症、严重败血症或感染性休克情况。
在研究期间，826名患者入住了重症监护病房。其中，421名（51%）在社区发生败血症，361名（44%）在重症监护病房发生，44名（5%）在普通病房住院期间发生。253名患者（30.6%）有一个器官系统受累：20%有呼吸系统受累，其次是肾脏和中枢神经系统受累，分别为3.4%和2.7%。
在我们的败血症患者队列中，重症监护病房中治疗的败血症患病率与其他研究报告的相似，总体死亡率也相似。
