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[胰腺癌的动脉重建——手术技术演示]

[Arterial reconstruction in pancreatic carcinoma –demonstration of surgical techniques].

作者信息

Grützmann R, Kersting S, Distler M, Weitz J

机构信息

Klinik und Poliklinik für Viszeral-, Thorax- und Gefäßchirurgie, Universitätsklinikum Carl Gustav Carus Dresden, Deutschland.

Klinik für Allgemein-, Viszeral- und Gefäßchirurgie, RKK Klinikum - St. Josefskrankenhaus, Freiburg, Deutschland.

出版信息

Zentralbl Chir. 2014 Jun;139(3):261-4. doi: 10.1055/s-0034-1368573. Epub 2014 Jun 26.

Abstract

INTRODUCTION

For a highly selected group of patients, a complete resection (R0) of a pancreatic carcinoma including arterial resection and reconstruction can represent an advantage in survival. The expertise of the surgeon in vascular and pancreatic surgery as well as the proficiency of the entire surgical and anaesthesiological team and the appropriate infrastructure of the hospital are prerequisites for the success of such complex operations. Proximal and distal of the tumour, sufficient lengths of the vessels are needed for the vascular anastomoses. In this video, the principles of arterial resection and reconstruction are shown in two patients with advanced pancreatic carcinoma.

INDICATION

This procedure is indicated for locally advanced pancreatic carcinoma with arterial infiltration without distant metastasis after neoadjuvant therapy.

PROCEDURE

The procedure involves 2 steps: 1. pancreatic head resection with resection of the common hepatic artery and end-to-end anastomosis of the hepatic artery and portal vein resection; 2. left pancreatic resection including splenectomy; resection of the celiac trunk, the superior mesenteric artery; reinsertion of the superior mesenteric artery into the aorta; end-to-end anastomosis of the common hepatic artery with the stump of the celiac trunk.

CONCLUSION

Given the appropriate experience, technically demanding arterial resections and reconstructions in pancreatic carcinoma are feasible and can provide superior survival for the patient compared to palliative therapy.

摘要

引言

对于经过严格筛选的一组患者,胰腺癌的完整切除(R0),包括动脉切除和重建,可能在生存方面具有优势。外科医生在血管和胰腺手术方面的专业知识,以及整个手术和麻醉团队的熟练程度和医院适当的基础设施,是此类复杂手术成功的先决条件。在肿瘤的近端和远端,血管吻合需要足够长度的血管。在本视频中,两名晚期胰腺癌患者展示了动脉切除和重建的原则。

适应症

该手术适用于新辅助治疗后局部晚期胰腺癌伴动脉浸润且无远处转移的患者。

手术步骤

该手术包括两个步骤:1. 胰头切除,同时切除肝总动脉,并进行肝动脉与门静脉切除后的端端吻合;2. 左半胰腺切除,包括脾切除;切除腹腔干、肠系膜上动脉;将肠系膜上动脉重新植入主动脉;肝总动脉与腹腔干残端进行端端吻合。

结论

鉴于有适当的经验,胰腺癌中技术要求高的动脉切除和重建是可行的,与姑息治疗相比,可为患者提供更好的生存效果。

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