Miyake Yoshihiro, Ota Shin-ichi, Shibata Masashi, Nakajima Kazunari, Nishibayashi Yoshiaki
Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, 113-8656, Japan.
Org Biomol Chem. 2014 Aug 14;12(30):5594-6. doi: 10.1039/c4ob00957f. Epub 2014 Jun 26.
Reactions of primary and secondary benzylic chlorides with trifluoromethyltrimethylsilane in the presence of a catalytic amount of copper(i) thiophene-2-carboxylate (CuTC) have been found to give the corresponding benzylic trifluoromethylated products in good to high yields.
已发现，在催化量的噻吩 - 2 - 羧酸铜（CuTC）存在下，伯苄基氯和仲苄基氯与三氟甲基三甲基硅烷反应，能以良好至高收率得到相应的苄基三氟甲基化产物。
