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铜催化三氟甲基化反应的进展

Progress in copper-catalyzed trifluoromethylation.

作者信息

Li Guan-Bao, Zhang Chao, Song Chun, Ma Yu-Dao

机构信息

School of Pharmaceutical sciences, Shandong University, 44 West Culture Road, Jinan 250012, PR China.

Department of chemistry, Shandong University, 27 Shanda South Road, Jinan 250100, PR China.

出版信息

Beilstein J Org Chem. 2018 Jan 17;14:155-181. doi: 10.3762/bjoc.14.11. eCollection 2018.

DOI:10.3762/bjoc.14.11
PMID:29441139
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5789444/
Abstract

The introduction of trifluoromethyl groups into organic molecules has attracted great attention in the past five years. In this review, we describe the recent efforts in the development of trifluoromethylation via copper catalysis using nucleophilic, electrophilic or radical trifluoromethylation reagents.

摘要

在过去五年中，将三氟甲基引入有机分子已引起了极大关注。在本综述中，我们描述了近期使用亲核、亲电或自由基三氟甲基化试剂通过铜催化进行三氟甲基化反应开发方面所做的努力。

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