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一个克里雅沙漠人群的父系和母系基因分析：克里雅人不是古格藏族的后裔。

Paternal and maternal genetic analysis of a desert Keriyan population: Keriyans are not the descendants of Guge Tibetans.

作者信息

Chen Kaixu, Ablimit Abdurahman, Ling Fengjun, Wu Weiwei, Shan Wenjuan, Qin Wenbei, Keweier Tuerhong, Zuo Hongli, Zhang Fuchun, Ma Zhenghai, Zheng Xiufen

机构信息

Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi, Xinjiang, China.

Beijing Entry-Exit Inspection and Quarantine Bureau, Beijing, China.

出版信息

PLoS One. 2014 Jun 26;9(6):e100479. doi: 10.1371/journal.pone.0100479. eCollection 2014.

DOI:10.1371/journal.pone.0100479
PMID:24968299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4072674/
Abstract

The Keriyan people live in an isolated village in the Taklimakan Desert in Xinjiang, Western China. The origin and migration of the Keriyans remains unclear. We studied paternal and maternal genetic variance through typing Y-STR loci and sequencing the complete control region of the mtDNA and compared them with other adjacent populations. Data show that the Keriyan have relatively low genetic diversity on both the paternal and maternal lineages and possess both European and Asian specific haplogroups, indicating Keriyan is an admixture population of West and East. There is a gender-bias in the extent of contribution from Europe vs. Asia to the Keriyan gene pool. Keriyans have more genetic affinity to Uyghurs than to Tibetans. The Keriyan are not the descendants of the Guge Tibetans.

摘要

克里雅人生活在中国西部新疆塔克拉玛干沙漠中一个与世隔绝的村庄里。克里雅人的起源和迁徙情况仍不清楚。我们通过对Y染色体短串联重复序列（Y-STR）位点进行分型以及对线粒体DNA（mtDNA）的完整控制区进行测序，研究了父系和母系遗传变异，并将其与其他相邻群体进行了比较。数据显示，克里雅人在父系和母系谱系上的遗传多样性相对较低，同时拥有欧洲和亚洲特有的单倍群，这表明克里雅人是东西方的混合群体。在欧洲和亚洲对克里雅人基因库的贡献程度上存在性别差异。克里雅人与维吾尔族的遗传亲缘关系比与藏族的更近。克里雅人不是古格藏族的后裔。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/c3e3b93fd347/pone.0100479.g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/755fa372a62d/pone.0100479.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/c728ca35ffca/pone.0100479.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/fa9ca182e792/pone.0100479.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/bb8f812d0d86/pone.0100479.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/0fe09ff5a8b6/pone.0100479.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/ca9d494aacd2/pone.0100479.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/c3e3b93fd347/pone.0100479.g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/755fa372a62d/pone.0100479.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/c728ca35ffca/pone.0100479.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/fa9ca182e792/pone.0100479.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/bb8f812d0d86/pone.0100479.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/0fe09ff5a8b6/pone.0100479.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/ca9d494aacd2/pone.0100479.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220a/4072674/c3e3b93fd347/pone.0100479.g007.jpg

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An updated tree of Y-chromosome Haplogroup O and revised phylogenetic positions of mutations P164 and PK4.Y 染色体单倍群 O 的更新树及突变 P164 和 PK4 的修正系统发育位置。
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High-throughput sequencing of complete human mtDNA genomes from the Caucasus and West Asia: high diversity and demographic inferences.
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BMC Evol Biol. 2011 Feb 15;11:46. doi: 10.1186/1471-2148-11-46.
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Evidence that a West-East admixed population lived in the Tarim Basin as early as the early Bronze Age.有证据表明，早在青铜时代早期，就有一个东西混合的人群居住在塔里木盆地。
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Early Eurasian migration traces in the Tarim Basin revealed by mtDNA polymorphisms.mtDNA 多态性揭示的塔里木盆地早期欧亚人群迁徙轨迹。
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