Archana B R, Prasad S R, Beena P M, Okade R, Sheela S R, Beeregowda Y C
Southeast Asian J Trop Med Public Health. 2014 Mar;45(2):430-4.
Screening women for syphilis during pregnancy and providing proper treatment are the cornerstones of congenital syphilis prevention. During 2008-2011, 6,221 pregnant women were screened for syphilis using the Rapid Plasma Reagin (RPR) and Treponema Pallidum Hemagglutination (TPHA) tests at R.L. Jalappa Hospital, Kolar, Karnataka, India. The seroprevalence of syphilis during pregnancy ranged from 0.57% to 0.78% during the study. Of the 35 women with a positive test, 26 (74.28%) were detected at the time of labor and 9 (25.71%) were detected during antenatal care. None of the women detected at the time of labor received penicillin therapy for syphilis. Adverse fetal outcomes due to untreated syphilis during pregnancy were seen in many of the cases. During the study 26 infants (3.69/1,000) were diagnosed with congenital syphilis. Our findings show detection and treatment of syphilis during pregnancy needs to be strengthened in the study area to reduce the incidence of congenital syphilis.
孕期对女性进行梅毒筛查并提供适当治疗是预防先天性梅毒的基石。2008年至2011年期间，在印度卡纳塔克邦科拉尔的R.L.贾拉帕医院，使用快速血浆反应素（RPR）和梅毒螺旋体血凝试验（TPHA）对6221名孕妇进行了梅毒筛查。研究期间，孕期梅毒血清阳性率在0.57%至0.78%之间。在35名检测呈阳性的女性中，26名（74.28%）在分娩时被检测出，9名（25.71%）在产前检查时被检测出。在分娩时检测出的女性中，没有一人接受过梅毒青霉素治疗。许多病例中都出现了孕期未治疗梅毒导致的不良胎儿结局。研究期间，26名婴儿（3.69/1000）被诊断为先天性梅毒。我们的研究结果表明，研究区域需要加强孕期梅毒的检测和治疗，以降低先天性梅毒的发病率。
