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制定新的国际 EQ-5D-5L 估值议定书的方法学研究方案。

A program of methodological research to arrive at the new international EQ-5D-5L valuation protocol.

机构信息

Institute for Medical Technology Assessment, Institute of Health Policy and Management, Erasmus University Rotterdam, Rotterdam, The Netherlands; EuroQol Group Foundation, Rotterdam, The Netherlands.

Office of Health Economics, London, UK.

出版信息

Value Health. 2014 Jun;17(4):445-53. doi: 10.1016/j.jval.2014.04.002.

DOI:10.1016/j.jval.2014.04.002
PMID:24969006
Abstract

OBJECTIVES

To describe the research that has been undertaken by the EuroQol Group to improve current methods for health state valuation, to summarize the results of an extensive international pilot program, and to outline the key elements of the five-level EuroQol five-dimensional (EQ-5D-5L) questionnaire valuation protocol, which is the culmination of that work.

METHODS

To improve on methods of health state valuation for the EQ-5D-5L questionnaire, we investigated the performance of different variants of time trade-off and discrete choice tasks in a multinational setting. We also investigated the effect of three modes of administration on health state valuation: group interviews, online self-completion, and face-to-face interviews.

RESULTS

The research program provided the basis for the EQ-5D-5L questionnaire valuation protocol. Two different types of tasks are included to derive preferences: a newly developed composite time trade-off task and a forced-choice paired comparisons discrete choice task. Furthermore, standardized blocked designs for the selection of the states to be valued by participants were created and implemented together with all other elements of the valuation protocol in a digital aid, the EuroQol Valuation Technology, which was developed in conjunction with the protocol.

CONCLUSIONS

The EuroQol Group has developed a standard protocol, with accompanying digital aid and interviewer training materials, that can be used to create value sets for the EQ-5D-5L questionnaire. The use of a well-described, consistent protocol across all countries enhances the comparability of value sets between countries, and allows the exploration of the influence of cultural and other factors on health state values.

摘要

目的

描述欧洲质量群组为改进当前健康状况估值方法所开展的研究,总结广泛国际试点计划的结果,并概述五级欧洲质量群组五维健康量表(EQ-5D-5L)问卷估值方案的关键要素,这是该工作的成果。

方法

为改进 EQ-5D-5L 问卷的健康状况估值方法,我们在跨国环境中研究了不同类型时间权衡和离散选择任务的表现。我们还研究了三种管理模式对健康状况估值的影响:小组访谈、在线自我完成和面对面访谈。

结果

该研究计划为 EQ-5D-5L 问卷估值方案提供了基础。纳入了两种不同类型的任务来推导偏好:新开发的复合时间权衡任务和强制选择配对比较离散选择任务。此外,为参与者选择要估值的状态创建并实施了标准化的分组设计,以及估值方案的所有其他要素都包含在一个名为 EuroQol 估值技术的数字辅助工具中,该工具是与方案一起开发的。

结论

欧洲质量群组已经开发了一个标准方案,包括配套的数字辅助工具和访谈员培训材料,可用于为 EQ-5D-5L 问卷创建价值集。在所有国家使用描述良好、一致的方案可增强国家间价值集的可比性,并允许探索文化和其他因素对健康状况值的影响。

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