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癌症治疗的未来:选择可能对PD1/L1阻断疗法有反应的患者。

The future of cancer therapy: selecting patients likely to respond to PD1/L1 blockade.

作者信息

Ribas Antoni, Tumeh Paul C

机构信息

Division of Hematology-Oncology, Department of Medicine, University of California Los Angeles, Los Angeles, California. Department of Surgery, University of California Los Angeles, Los Angeles, California. Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California. Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California.

Division of Dermatology, Department of Medicine, University of California Los Angeles, Los Angeles, California.

出版信息

Clin Cancer Res. 2014 Oct 1;20(19):4982-4. doi: 10.1158/1078-0432.CCR-14-0933. Epub 2014 Jun 26.

Abstract

It is conceivable that, in the near future, an assay that defines the likelihood of a patient with advanced cancer to respond to immunotherapy based on PD1/L1 blockade will be the initial decision point to select the treatment of patients with any cancer type.

摘要

可以想象,在不久的将来,一种基于PD1/L1阻断来确定晚期癌症患者对免疫疗法反应可能性的检测方法,将成为选择任何癌症类型患者治疗方案的初始决策点。

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