美沙酮维持治疗对阿片类药物依赖患者人体测量指标的影响。
Effect of methadone maintenance therapy on anthropometric indices in opioid dependent patients.
作者信息
Montazerifar Farzaneh, Karajibani Mansour, Lashkaripour Kobra
机构信息
Pregnancy Health Research Center, Zahedan University of Medical Sciences, Zahedan, IR Iran ; Health Promotion Research Center Zahedan University of Medical Sciences, Zahedan, IR Iran ; Department of Nutrition, School of Medicine, Zahedan University of Medical Sciences, Zahedan, IR Iran.
Department of Psychiatry ,Baharan Psychiatric Hospital, Zahedan University of Medical Sciences, Zahedan, IR Iran.
出版信息
Int J High Risk Behav Addict. 2012 Fall;1(3):100-3. doi: 10.5812/ijhrba.4968. Epub 2012 Nov 26.
BACKGROUND
Opium abuse significantly affects the nutritional status of users and frequently leads to undernourishment. Methadone maintenance therapy has been used as one of the possible ways to prevent of infection diseases such as HIV and hepatitis B and C and improve the quality of life in opioid-dependent patients.
OBJECTIVES
The aim of this study was to assess the anthropometric and socio-demographic characteristics of opium addicted persons before and after 8 weeks of methadone maintenance therapy (MMT).
PATIENTS AND METHODS
A clinical cross-sectional study was carried out on 55 opium users (15 women and 40 men; mean aged 31.6 ± 10 years), dependent on opium and its derivatives at the Addiction Treatment Clinic of the Baharan psychiatric Hospital, Zahedan, Sistan and Baluchistan Province, Iran, in 2011. The patients were examined before and after 8 weeks MMT. Weight and height of participants were taken and the body mass index (BMI) was calculated.
RESULTS
Body weight increased significantly from 61.4 ± 14.4 to 65.3 ± 14.2 kg and BMI from 21.4 ± 4.2 to 23 ± 5.6 (kg/m(2)) after 8 weeks of methadone maintenance therapy in opium users (P < 0.01). The percentages of underweight, overweight and obese patients were; 27.3%, 18.2% and 3.6%, respectively pre-MMT, and 12.7%, 18.2% and 7.2%, respectively after MMT.
CONCLUSIONS
The study shows that methadone Maintenance Therapy led to improvements in nutritional status.
背景
鸦片滥用严重影响使用者的营养状况，并常常导致营养不良。美沙酮维持治疗已被用作预防诸如艾滋病毒和乙型及丙型肝炎等传染病以及改善阿片类药物依赖患者生活质量的可能方法之一。
目的
本研究的目的是评估美沙酮维持治疗（MMT）8周前后鸦片成瘾者的人体测量和社会人口学特征。
患者与方法
2011年，在伊朗锡斯坦-俾路支斯坦省扎黑丹市巴哈兰精神病医院成瘾治疗诊所，对55名依赖鸦片及其衍生物的使用者（15名女性和40名男性；平均年龄31.6±10岁）进行了一项临床横断面研究。在MMT 8周前后对患者进行检查。测量参与者的体重和身高，并计算体重指数（BMI）。
结果
鸦片使用者在接受8周美沙酮维持治疗后，体重从61.4±14.4显著增加至65.3±14.2 kg，BMI从21.4±4.2增加至23±5.6（kg/m²）（P<0.01）。治疗前体重过轻、超重和肥胖患者的百分比分别为27.3%、18.2%和3.6%，治疗后分别为12.7%、18.2%和7.2%。
结论
该研究表明美沙酮维持治疗可改善营养状况。
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