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青少年的心血管健康:与肥胖及代谢异常的关联

Cardiovascular fitness in youth: association with obesity and metabolic abnormalities.

作者信息

Guixeres Jaime, Redon Pau, Saiz Javier, Alvarez Julio, Torró Maria Isabel, Cantero Laura, Lurbe Empar

机构信息

Polytechnical University of Valencia, Spain..

Pediatric Department, Consorcio Hospital General Universitario, University of Valencia, Valencia, Spain..

出版信息

Nutr Hosp. 2014 Jun 1;29(6):1290-7. doi: 10.3305/nh.2014.29.6.7383.

DOI:10.3305/nh.2014.29.6.7383
PMID:24972465
Abstract

UNLABELLED

Therapies currently implemented for obesity are focused on nutritional aspects and on physical activity. In order to make physical activity a positive therapy instead of triggering disabilities it is relevant to accurately assess cardiovascular fitness.

OBJECTIVE

To assess the cardiovascular fitness by measuring the peak oxygen consumption and to asses their relationship with classical cardiometabolic parameters.

METHODS

A modified Balke protocol was applied to one hundred and twenty-six Caucasians (60% males), ranging between 9 and 16 years old, who underwent an assessment of obesity. The non-obese group consisted of healthy age and sex matched subjects who were invited to participate from the general population.

RESULTS

Significant differences in consumption of oxygen peak between non-obese and obese individuals were observed. In contrast, no significant differences existed between the categories of obesity. Furthermore in obese subjects consumption of oxygen peak was inversely correlated with parameters of cardiometabolic risk, particularly insulin and HOMA index. In addition, two predictive equations of consumption of oxygen peak, with an R2 of 0.74 and 0.84, respectively, have been developed.

CONCLUSION

The consumption of oxygen peak is a relevant clinical parameter that should be included in the routine clinical assessment of obese subjects. Therefore, it is crucial to make exercise tests more affordable which can be achieved by employing predictive equations.

摘要

未标注

目前用于治疗肥胖症的疗法主要集中在营养方面和体育活动上。为了使体育活动成为一种积极的治疗方法而非引发残疾,准确评估心血管健康状况至关重要。

目的

通过测量峰值耗氧量来评估心血管健康状况,并评估其与经典心脏代谢参数的关系。

方法

对126名9至16岁的高加索人(60%为男性)应用改良的巴尔克方案,这些人接受了肥胖评估。非肥胖组由从普通人群中邀请的年龄和性别匹配的健康受试者组成。

结果

观察到非肥胖者和肥胖者之间峰值耗氧量存在显著差异。相比之下,肥胖类别之间不存在显著差异。此外,在肥胖受试者中,峰值耗氧量与心脏代谢风险参数,特别是胰岛素和HOMA指数呈负相关。此外,还建立了两个峰值耗氧量的预测方程,其R2分别为0.74和0.84。

结论

峰值耗氧量是一个相关的临床参数,应纳入肥胖受试者的常规临床评估中。因此,通过采用预测方程使运动测试更经济实惠至关重要。

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