Zhang Xiao-Dong, Wang Guo-Zhu, Zhuang Ru-Jie
Zhongguo Gu Shang. 2014 Mar;27(3):213-6.
To analyzed the relationship between lumbar endplate Modic area changes rate and low back pain by measuring MRI T2 sagittal image of lumbar endplate Modic area changes rate.
From December 2011 to June 2012,70 patients with low back pain in operation were evaluated on pain by VAS and function by JOA,and examined by MRI including 39 males and 31 females with an average age of (51.00 +/- 11.89) years ranging from 29 to 72 years old. Among them, 54 cases had lumbar endplate Modic changes involving 15 cases in types Modic I ,21 cases in type Modic II, 11 cases in type Modic III ,mixed type Modic in 7 cases (eliminated for too few cases). Modic area changes and corresponding vertebral area were measured on MRI T2 median sagittal. The areas of two ways were compared to yield the rate of changes for Modic, for multisegmental Modic changes to calculate the total ratios. A correlation was observed among JOA, VAS and the rate of Modic changes.
The correlation coefficient of change rate of Modic I with JOA score was r = -0.308, P = 0.048 < 0.05, there was a negative correlation;the correlation coefficient of change rate of Modic I with VAS scores was r = 0.428,P = 0.021 < 0.05, there was a positive correlation. The correlation coefficient of change rate of Modic II with JOA score was r = -0.375, P = 0.043 < 0.05, there was a negative correlation;the correlation coefficient of change rate of Modic II with VAS score was r = 0.352, P = 0.041 < 0.05, there was a positive correlation. The area change rate of Modic III had no significant correlation with low back pain degree (P > 0.05).
Modic I and II area changes rate of of patients with low back pain is closely related to the degree of pain low back pain, Modic III area changes rate is not significant correlated to the degree of lower back pain.
通过测量腰椎终板Modic区变化率的MRI T2矢状位图像，分析腰椎终板Modic区变化率与腰痛之间的关系。
2011年12月至2012年6月，对70例接受手术的腰痛患者采用视觉模拟评分法（VAS）评估疼痛情况，采用日本骨科学会（JOA）评分法评估功能情况，并进行MRI检查，其中男性39例，女性31例，平均年龄（51.00±11.89）岁，年龄范围为29至72岁。其中54例存在腰椎终板Modic改变，包括Modic I型15例、Modic II型21例、Modic III型11例、混合型7例（因病例过少予以排除）。在MRI T2正中矢状位上测量Modic区变化及相应椎体面积。比较两种面积以得出Modic区变化率，对于多节段Modic改变计算总变化率。观察JOA评分、VAS评分与Modic变化率之间的相关性。
Modic I型变化率与JOA评分的相关系数r=-0.308，P=0.048<0.05，呈负相关；Modic I型变化率与VAS评分的相关系数r=0.428，P=0.021<0.05，呈正相关。Modic II型变化率与JOA评分的相关系数r=-0.375，P=0.043<0.05，呈负相关；Modic II型变化率与VAS评分的相关系数r=0.352，P=0.041<0.05，呈正相关。Modic III型面积变化率与腰痛程度无显著相关性（P>0.05）。
腰痛患者的Modic I型和II型面积变化率与腰痛程度密切相关，Modic III型面积变化率与腰痛程度无显著相关性。
