Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.
Spine (Phila Pa 1976). 2012 Sep 15;37(20):1756-62. doi: 10.1097/BRS.0b013e318257ffce.
A cross-sectional observational study.
To investigate whether there is a difference in findings of lumbar Modic changes in low-field (0.3 T) magnetic resonance imaging (MRI) compared with high-field (1.5 T).
It is a challenge to give patients with low back pain a specific diagnosis. Modic changes as seen on MRI have been reported to be a possible source of pain. However, it is unclear whether the diagnosis is independent on the field strength.
Twenty patients with Modic changes, 11 women and 9 men (mean age, 53.6 yr; range, 29-81 yr), with or without sciatica, seen in a Danish outpatient low back pain clinic were included. All patients obtained MRI scans on both a high-field and a low-field MRI scanner. Two radiologists evaluated all lumbar endplates independently, using a standardized evaluation protocol. Kappa statistics were used to analyze the interobserver reproducibility. We used paired t test to analyze the difference between low- and high-field MRI.
The total number of Modic changes diagnosed with high-field MRI was significantly higher than that with low-field MRI. However, 3 to 4 times as many Modic type 1 changes were found with low-field MRI compared with high-field MRI. Contrarily, with high-field MRI type 2 changes were diagnosed twice as often.
There was a significant difference between low- and high-field MRI regarding the overall prevalence of any Modic change, but this had opposite directions for types 1 and 2: type 2 dominated in high field and conversely in high field [corrected]. The type of MRI unit should be taken into consideration when diagnosing patients with Modic changes
一项横断面观察性研究。
探讨低场（0.3T）磁共振成像（MRI）与高场（1.5T）MRI 相比，腰椎 Modic 改变的发现是否存在差异。
为腰痛患者做出明确诊断颇具挑战。MRI 所见的 Modic 改变被认为是疼痛的一个可能来源。然而，诊断是否独立于磁场强度尚不清楚。
20 例 Modic 改变患者（11 名女性，9 名男性；平均年龄 53.6 岁；年龄范围 29-81 岁），包括有或无坐骨神经痛的患者，在丹麦门诊腰痛诊所接受检查。所有患者均在高场和低场 MRI 扫描仪上进行 MRI 扫描。两名放射科医生使用标准化评估方案独立评估所有腰椎终板。使用 Kappa 统计分析观察者间的可重复性。我们使用配对 t 检验分析低场和高场 MRI 之间的差异。
高场 MRI 诊断的 Modic 改变总数明显高于低场 MRI。然而，低场 MRI 比高场 MRI 发现的 Modic 1 型改变多 3 到 4 倍。相反，高场 MRI 诊断 2 型改变的次数是低场 MRI 的两倍。
低场和高场 MRI 之间在任何 Modic 改变的总体流行率方面存在显著差异，但 1 型和 2 型的差异方向相反：2 型在高场中占主导地位，反之亦然。在诊断 Modic 改变患者时，应考虑 MRI 设备的类型。
