急性金刚烷胺对可卡因渴求影响的双盲评估。
Double-blind evaluation of the effect of acute amantadine on cocaine craving.
作者信息
Gawin F H, Morgan C, Kosten T R, Kleber H D
机构信息
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519.
出版信息
Psychopharmacology (Berl). 1989;97(3):402-3. doi: 10.1007/BF00439458.
PMID:2497490
Abstract
Single doses of amantadine hydrochloride and placebo were administered in a double-blind cross-over design on separate days to ten actively craving cocaine abusers in treatment. Pharmacological treatment did influence cocaine craving, but amantadine was less effective than placebo.
摘要
采用双盲交叉设计，在不同日期给10名积极渴望戒除可卡因的滥用者分别单次服用盐酸金刚烷胺和安慰剂进行治疗。药物治疗确实影响了对可卡因的渴望，但金刚烷胺的效果不如安慰剂。
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