Fujikawa Hiroshi, Sakha Mohammad Z
Laboratory of Veterinary Public Health, Faculty of Agriculture Tokyo University of Agriculture and Technology.
Biocontrol Sci. 2014;19(2):89-92. doi: 10.4265/bio.19.89.
Prediction of microbial growth in mixed culture was studied with a competition model that we had developed recently. The model, which is composed of the new logistic model and the Lotka-Volterra model, is shown to successfully describe the microbial growth of two species in mixed culture using Staphylococcus aureus, Escherichia coli, and Salmonella. With the parameter values of the model obtained from the experimental data on monoculture and mixed culture with two species, it then succeeded in predicting the simultaneous growth of the three species in mixed culture inoculated with various cell concentrations. To our knowledge, it is the first time for a prediction model for multiple (three) microbial species to be reported. The model, which is not built on any premise for specific microorganisms, may become a basic competition model for microorganisms in food and food materials.
利用我们最近开发的竞争模型研究了混合培养中微生物生长的预测。该模型由新的逻辑模型和洛特卡 - 沃尔泰拉模型组成，已证明其能成功描述使用金黄色葡萄球菌、大肠杆菌和沙门氏菌进行的两种菌混合培养中的微生物生长情况。根据从单一培养和两种菌混合培养的实验数据获得的模型参数值，该模型成功预测了接种不同细胞浓度的三种菌在混合培养中的同时生长情况。据我们所知，这是首次报道针对多种（三种）微生物的预测模型。该模型并非基于特定微生物的任何前提构建，可能会成为食品和食品原料中微生物的基本竞争模型。
