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三个社区队列中16岁女孩的清除行为患病率及其与负面结果的关联。

Prevalence of purging at age 16 and associations with negative outcomes among girls in three community-based cohorts.

作者信息

Solmi Francesca, Sonneville Kendrin R, Easter Abigail, Horton Nicholas J, Crosby Ross D, Treasure Janet, Rodriguez Alina, Jarvelin Marjo-Riitta, Field Alison E, Micali Nadia

机构信息

Behavioural & Brain Sciences Unit, Institute of Child Health, University College London, London, UK.

出版信息

J Child Psychol Psychiatry. 2015 Jan;56(1):87-96. doi: 10.1111/jcpp.12283. Epub 2014 Jun 27.

Abstract

BACKGROUND

The comorbidity of purging behaviours, such as vomiting, inappropriate use of laxatives, diuretics or slimming medications, has been examined in literature. However, most studies do not include adolescents, individuals who purge in the absence of binge eating, or those purging at subclinical frequency. This study examines the prevalence of purging among 16-year-old girls across three countries and their association with substance use and psychological comorbidity.

METHODS

Data were obtained by questionnaire in 3 population-based cohorts (Avon Longitudinal Study of Parents and Children (ALSPAC), United Kingdom, n = 1,608; Growing Up Today Study (GUTS), USA, n = 3,504; North Finland Birth Cohort (NFBC85/86), Finland, n = 2,306). Multivariate logistic regressions were employed to estimate associations between purging and outcomes. Four models were fit adjusting for binge eating and potential confounders of these associations.

RESULTS

In ALSPAC, 9.7% of girls reported purging in the 12-months prior to assessment, 7.3% in GUTS, and 3.5% in NFBC. In all 3 cohorts, purging was associated with adverse outcomes such as binge drinking (ALSPAC: odds ratio (OR) = 2.0, 95% confidence interval (CI) = 1.4-2.9; GUTS: OR = 2.5, 95% CI = 1.5-4.0; NFBC: OR = 1.7, 95% CI = 1.0-2.8), drug use (ALSPAC: OR = 2.9, 95% CI = 1.8-4.7; GUTS: OR = 4.5, 95% CI = 2.8-7.3; NFBC: OR = 4.1, 95% CI = 2.6-6.6), depressive symptoms in ALSPAC (OR = 2.2, 95% CI = 1.5-3.1) and GUTS(OR = 3.7, 95% CI = 2.2-6.3), and several psychopathology measures including clinical anxiety/depression in NFBC (OR = 11.2, 95% CI = 3.9, 31.7).

CONCLUSIONS

Results show a higher prevalence of purging behaviours among girls in the United Kingdom compared to those in the United States and Finland. Our findings support evidence highlighting that purging in adolescence is associated with negative outcomes, independent of its frequency and binge eating.

摘要

背景

文献中已对诸如呕吐、不适当使用泻药、利尿剂或减肥药物等清除行为的合并症进行了研究。然而,大多数研究未纳入青少年、在无暴饮暴食情况下进行清除行为的个体,或清除频率处于亚临床水平的个体。本研究调查了三个国家16岁女孩中清除行为的患病率及其与物质使用和心理合并症的关联。

方法

通过问卷调查从3个基于人群的队列中获取数据(英国埃文父母与儿童纵向研究(ALSPAC),n = 1608;美国今日成长研究(GUTS),n = 3504;芬兰北芬兰出生队列(NFBC85/86),n = 2306)。采用多变量逻辑回归来估计清除行为与各项结果之间的关联。拟合了四个模型,对暴饮暴食和这些关联的潜在混杂因素进行了调整。

结果

在ALSPAC中,9.7%的女孩报告在评估前12个月内有清除行为,在GUTS中为7.3%,在NFBC中为3.5%。在所有3个队列中,清除行为与不良后果相关,如暴饮(ALSPAC:比值比(OR)= 2.0,95%置信区间(CI)= 1.4 - 2.9;GUTS:OR = 2.5,95% CI = 1.5 - 4.0;NFBC:OR = 1.7,95% CI = 1.0 - 2.8)、药物使用(ALSPAC:OR = 2.9,95% CI = 1.8 - 4.7;GUTS:OR = 4.5,95% CI = 2.8 - 7.3;NFBC:OR = 4.1,95% CI = 2.6 - 6.6)、ALSPAC中的抑郁症状(OR = 2.2,95% CI = 1.5 - 3.1)和GUTS中的抑郁症状(OR = 3.7,95% CI = 2.2 - 6.3),以及NFBC中的几种精神病理学指标,包括临床焦虑/抑郁(OR = 11.2,95% CI = 3.9,31.7)。

结论

结果显示,与美国和芬兰的女孩相比,英国女孩中清除行为的患病率更高。我们的研究结果支持了相关证据,即强调青少年中的清除行为与负面后果相关,且与清除频率和暴饮暴食无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d577/4303957/7d03f4c6b986/jcpp0056-0087-f1.jpg

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