University of Texas Medical School , 6431 Fannin Street, Suite 6.018, Houston, TX 77030 , USA.
Expert Opin Pharmacother. 2014 Sep;15(13):1827-36. doi: 10.1517/14656566.2014.934809. Epub 2014 Jun 30.
Erectile dysfunction (ED) is one of the most common complications of diabetes. The complex pathophysiology of this disease makes it difficult to create clinical treatments tailored specifically for diabetic patients.
This article will provide an update of both medical and surgical treatment approaches for diabetic ED, as well as discuss established treatments that are the cornerstone of this field.
Currently, PDE type 5 inhibitors represent the first-line treatment for all patients with ED. In the interim since this article's first publication several new PDE5 inhibitors have come to market. Several others that were previously on the market are now available for daily dosing. Analysis of both testosterone level and hemoglobin A1c is an essential part of treatment. Intracavernosal injections and vacuum constriction devices remain safe, and are highly effective treatment options. The implantable penile prosthesis remains a safe, and definitive treatment modality for those patients with refractory ED. Over the coming years as the understanding of the underlying causes of diabetic ED continues, the development of new, noninvasive, but effective medical treatments will lead to even more options for the treatment of this difficult disease.
勃起功能障碍（ED）是糖尿病最常见的并发症之一。这种疾病复杂的病理生理学使得很难为糖尿病患者量身定制具体的临床治疗方法。
本文将提供糖尿病 ED 的医学和手术治疗方法的最新更新，并讨论该领域的基石既定治疗方法。
目前，PDE 类型 5 抑制剂是所有 ED 患者的一线治疗药物。自本文首次发表以来的这段时间里，几种新的 PDE5 抑制剂已经上市。以前市场上的几种药物现在也可以每天服用。分析睾丸激素水平和血红蛋白 A1c 是治疗的重要组成部分。阴茎海绵体内注射和真空勃起装置仍然是安全且非常有效的治疗选择。对于那些难治性 ED 患者，可植入阴茎假体仍然是一种安全且确定的治疗方式。在未来几年，随着对糖尿病 ED 潜在原因的理解不断深入，新的非侵入性但有效的医学治疗方法的发展将为这种棘手疾病的治疗提供更多选择。
