Krzastek Sarah C, Bopp Justin, Smith Ryan P, Kovac Jason R
Department of Urology, University of Virginia, Charlottesville, Virginia, USA.
Men's Health Center, Indianapolis, Indiana, USA.
F1000Res. 2019 Jan 25;8. doi: 10.12688/f1000research.16576.1. eCollection 2019.
Erectile dysfunction (ED) is important to a man's well-being and health, since it not only affects the individual but also causes strain on a couple's lifestyle and relationship. There are multiple non-invasive treatments that exist for ED including lifestyle changes, oral medications (phosphodiesterase type 5 inhibitors), vacuum-assisted erectile devices, and intraurethral suppositories. While lifestyle changes and oral medications are typically first-line treatments for ED, more-invasive treatments including intracavernosal injections and surgically implanted prosthetic devices may be required for the management of complex cases. Additionally, novel therapies are currently being developed, and future treatment options may include shock-wave therapy, external prosthetic devices, and injection of stem cells or platelet-rich plasma. The current manuscript seeks to highlight advances in management and may eventually alter the treatment paradigm to allow more-inclusive care pathways.
勃起功能障碍（ED）对男性的幸福和健康至关重要，因为它不仅影响个人，还会给夫妻的生活方式和关系带来压力。ED有多种非侵入性治疗方法，包括生活方式改变、口服药物（5型磷酸二酯酶抑制剂）、真空辅助勃起装置和尿道内栓剂。虽然生活方式改变和口服药物通常是ED的一线治疗方法，但对于复杂病例的管理，可能需要更具侵入性的治疗方法，包括海绵体内注射和手术植入假体装置。此外，目前正在开发新的疗法，未来的治疗选择可能包括冲击波疗法、外部假体装置以及注射干细胞或富含血小板的血浆。本手稿旨在突出管理方面的进展，并最终可能改变治疗模式，以实现更具包容性的护理途径。
