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使用高阶有限元对心脏电传播进行高效模拟。

Efficient simulation of cardiac electrical propagation using high order finite elements.

作者信息

Arthurs Christopher J, Bishop Martin J, Kay David

机构信息

Department of Computer Science, University of Oxford, Oxford, United Kingdom.

Department of Computer Science, University of Oxford, Oxford, United Kingdom ; Department of Biomedical Engineering, King's College London, London, United Kingdom.

出版信息

J Comput Phys. 2012 May 20;231(10):3946-3962. doi: 10.1016/j.jcp.2012.01.037.

Abstract

We present an application of high order hierarchical finite elements for the efficient approximation of solutions to the cardiac monodomain problem. We detail the hurdles which must be overcome in order to achieve theoretically-optimal errors in the approximations generated, including the choice of method for approximating the solution to the cardiac cell model component. We place our work on a solid theoretical foundation and show that it can greatly improve the accuracy in the approximation which can be achieved in a given amount of processor time. Our results demonstrate superior accuracy over linear finite elements at a cheaper computational cost and thus indicate the potential indispensability of our approach for large-scale cardiac simulation.

摘要

我们展示了高阶分层有限元在心脏单域问题解的高效逼近中的应用。我们详细阐述了为在生成的逼近中实现理论上最优的误差必须克服的障碍,包括逼近心脏细胞模型组件解的方法选择。我们将我们的工作建立在坚实的理论基础上,并表明它可以在给定的处理器时间内大大提高逼近的精度。我们的结果表明,在计算成本更低的情况下,我们的方法比线性有限元具有更高的精度,因此表明我们的方法在大规模心脏模拟中可能不可或缺。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1072/4067136/a8a6a6ac4a02/gr1.jpg

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