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Acellular pertussis vaccine use in risk groups (adolescents, pregnant women, newborns and health care workers): a review of evidences and recommendations.无细胞百白破疫苗在风险人群(青少年、孕妇、新生儿和医护人员)中的使用:证据回顾与建议。
Vaccine. 2012 Jul 27;30(35):5179-90. doi: 10.1016/j.vaccine.2012.06.005. Epub 2012 Jun 15.
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Improving childhood vaccination rates.提高儿童疫苗接种率。
N Engl J Med. 2012 Feb 2;366(5):391-3. doi: 10.1056/NEJMp1113008.
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Duration of maternally derived antibody against measles: a seroepidemiological study of infants aged under 8 months in Qinghai, China.母体麻疹抗体持续时间:中国青海 8 月龄以下婴儿血清流行病学研究。
Vaccine. 2012 Jan 17;30(4):752-7. doi: 10.1016/j.vaccine.2011.11.078. Epub 2011 Nov 29.
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Varicella in infants after implementation of the US varicella vaccination program.美国水痘疫苗接种计划实施后婴儿水痘。
Pediatrics. 2011 Dec;128(6):1071-7. doi: 10.1542/peds.2011-0017. Epub 2011 Nov 28.
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Impact of universal vaccination on the epidemiology of varicella in Veneto, Italy.意大利威尼托地区常规疫苗接种对水痘流行病学的影响。
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The impact of adolescent pertussis immunization, 2004-2009: lessons from Australia.青少年百日咳免疫接种的影响,2004-2009:来自澳大利亚的经验教训。
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Maternal immunization with tetanus-diphtheria-pertussis vaccine: effect on maternal and neonatal serum antibody levels.母亲接种破伤风白喉无细胞百日咳联合疫苗:对母体和新生儿血清抗体水平的影响。
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Early waning of maternal measles antibodies in era of measles elimination: longitudinal study.消除麻疹时代母体麻疹抗体的早期衰减:纵向研究。
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Pertussis disease burden in the household: how to protect young infants.百日咳疾病负担在家庭中:如何保护婴幼儿。
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传染病与疫苗接种策略:如何保护“无法得到保护的人群”?

Infectious diseases and vaccination strategies: how to protect the "unprotectable"?

作者信息

Bozzola Elena, Bozzola Mauro, Calcaterra Valeria, Barberi Salvatore, Villani Alberto

机构信息

Department of Pediatrics, Pediatric and Infectious Disease Unit, Bambino Gesù Children's Hospital, 00100 Rome, Italy.

Department of Internal Medicine, University of Pavia, 27100 Pavia, Italy.

出版信息

ISRN Prev Med. 2013 Apr 3;2013:765354. doi: 10.5402/2013/765354. eCollection 2013.

DOI:10.5402/2013/765354
PMID:24977097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4062883/
Abstract

Introduction. The circulation of infectious diseases puts small infants too young to be vaccinated at risk of morbidity and mortality, often requiring prolonged hospitalization. Material and Methods. We have reviewed the medical records of children not eligible for vaccination because of age, admitted to hospital for pertussis, measles, or varicella from February 1, 2010, till February 1, 2012. Results. Of the case records scrutinized, 21 were hospitalized for pertussis, 18 for measles, and 32 for varicella. Out of them, 42%, 66%, and 78% diagnosed with, respectively, pertussis, measles, and varicella had a complicated course of the disease. Discussion. To avoid infectious disease circulation, childhood immunization strategies should be adopted, such as vaccination of healthcare givers, adult household contacts, and parents planning to have, or who have had, a newborn baby.

摘要

引言。传染病的传播使太小而无法接种疫苗的婴儿面临发病和死亡风险,通常需要长期住院治疗。材料与方法。我们回顾了2010年2月1日至2012年2月1日期间因年龄原因不适合接种疫苗、因百日咳、麻疹或水痘入院治疗的儿童的病历。结果。在审查的病例记录中,21例因百日咳住院,18例因麻疹住院,32例因水痘住院。其中,分别被诊断为百日咳、麻疹和水痘的病例中,有42%、66%和78%的病情较为复杂。讨论。为避免传染病传播,应采取儿童免疫策略,如对医护人员、成年家庭接触者以及计划生育或已生育新生儿的父母进行疫苗接种。