Engel J M, Blair N P, Harris D, Baker D S
Department of Ophthalmology, University of Illinois, Chicago, College of Medicine.
Arch Ophthalmol. 1989 May;107(5):731-4. doi: 10.1001/archopht.1989.01070010749039.
Hemorrhage and retinal perforation are two sight-threatening complications associated with techniques employed to drain subretinal fluid in rhegmatogenous retinal detachment. We hypothesized that the carbon dioxide (CO2) laser would reduce these complications because of its cauterizing action and high absorption in water. The CO2 laser was compared with a conventional technique of using a penetrating diathermy electrode to drain subretinal fluid in rabbits with experimentally detached retinas. No hemorrhage occurred in 223 drainage trials using the CO2 laser, whereas hemorrhage occurred in 21 (4.8%) of 434 trials using the penetrating diathermy electrode. Furthermore, a depth of saline of only 45 microns protected the retina from perforation at CO2 laser dose adequate for drainage. These results indicate that further evaluation of the CO2 laser in treating human retinal detachment is warranted.
出血和视网膜穿孔是孔源性视网膜脱离手术中用于引流视网膜下液的技术所导致的两种威胁视力的并发症。我们推测二氧化碳（CO₂）激光由于其烧灼作用和在水中的高吸收率，会减少这些并发症。在实验性视网膜脱离的兔子中，将CO₂激光与使用穿透性透热电极引流视网膜下液的传统技术进行了比较。使用CO₂激光进行的223次引流试验中未发生出血，而使用穿透性透热电极进行的434次试验中有21次（4.8%）发生了出血。此外，在足以进行引流的CO₂激光剂量下，仅45微米厚的盐水层就能保护视网膜不被穿孔。这些结果表明，有必要对CO₂激光治疗人类视网膜脱离进行进一步评估。
