肉毒杆菌神经毒素A治疗特发性软骨溶解症：两例报告

Botulinum neurotoxin-A in idiopathic chondrolysis: a report of two cases.

作者信息

Khoshhal Khalid I, Awaad Yasser, Abbak Alshahid A

机构信息

aOrthopedic Department, College of Medicine, Taibah University, Almadinah Almunawwarah bPediatric Neurology Department, National Neuroscience Institute cOrthopedic Surgery Division, Department of Surgery, King Fahad Medical City, Riyadh, Saudi Arabia.

出版信息

J Pediatr Orthop B. 2014 Sep;23(5):441-6. doi: 10.1097/BPB.0000000000000076.

DOI:10.1097/BPB.0000000000000076

PMID:24977652

Abstract

Two cases of idiopathic chondrolysis were treated by botulinum neurotoxin-A injections, with a favorable outcome. The treatment consisted of botulinum neurotoxin-A injections, followed by an intensive rehabilitation program. No surgery was needed. Both patients were symptom-free and showed an extremely satisfactory range of motion. Radiographs indicated reconstitution of the joint space in both cases. We believe that botulinum neurotoxin-A injections combined with an intensive rehabilitation program may be considered a new potential management modality and is worth attempting and studying when one considers the results of previously published reports.

摘要

两例特发性关节溶解症患者接受了A型肉毒杆菌神经毒素注射治疗，结果良好。治疗包括A型肉毒杆菌神经毒素注射，随后进行强化康复计划。无需手术。两名患者均无症状，关节活动范围极为令人满意。X线片显示两例患者的关节间隙均已恢复。考虑到既往发表报告的结果，我们认为A型肉毒杆菌神经毒素注射联合强化康复计划可被视为一种新的潜在治疗方式，值得尝试和研究。