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1
Tetrahydroaminoacridine (THA) in Alzheimer's disease.四氢氨基吖啶（THA）与阿尔茨海默病
BMJ. 1989 Apr 1;298(6677):845-6. doi: 10.1136/bmj.298.6677.845.
2
Tacrine in the treatment of Alzheimer's disease. A clinical update and recent pharmacologic studies.他克林治疗阿尔茨海默病：临床进展与近期药理学研究
Eur Neurol. 1989;29 Suppl 3:28-32. doi: 10.1159/000116478.
3
The use of THA for Alzheimer's disease.全髋关节置换术在阿尔茨海默病中的应用。
Med J Aust. 1990 Jun 4;152(11):614. doi: 10.5694/j.1326-5377.1990.tb125404.x.
4
Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Français d'Etude de la Tetrahydroaminoacridine.他克林（四氢氨基吖啶；THA）与卵磷脂治疗阿尔茨海默型老年痴呆症：一项多中心试验。法国四氢氨基吖啶研究小组
BMJ. 1990 Feb 24;300(6723):495-9. doi: 10.1136/bmj.300.6723.495.
5
Clinical pharmacology of tetrahydroaminoacridine: a possible therapeutic agent Alzheimer's disease.
Int J Clin Pharmacol Ther Toxicol. 1989 Oct;27(10):478-85.
6
Tetrahydroaminoacridine and Alzheimer's disease.四氢氨基吖啶与阿尔茨海默病。
Lancet. 1987 Feb 21;1(8530):444-5.
7
Tetrahydroaminoacridine and Alzheimer's disease.四氢氨基吖啶与阿尔茨海默病。
Lancet. 1987 Feb 7;1(8528):322. doi: 10.1016/s0140-6736(87)92041-1.
8
Tetrahydroaminoacridine in Alzheimer's disease.四氢氨基吖啶与阿尔茨海默病
BMJ. 1989 Jun 10;298(6687):1579. doi: 10.1136/bmj.298.6687.1579-a.
9
Oral tetrahydroaminoacridine in the treatment of senile dementia, Alzheimer's type.
N Engl J Med. 1987 Jun 18;316(25):1603-5. doi: 10.1056/NEJM198706183162512.
10
Tacrine and lecithin in Alzheimer's disease.他克林与卵磷脂治疗阿尔茨海默病
BMJ. 1990 Apr 7;300(6729):939-40. doi: 10.1136/bmj.300.6729.939-a.

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1
Absorption, metabolism, and disposition of [14C]SDZ ENA 713, an acetylcholinesterase inhibitor, in minipigs following oral, intravenous, and dermal administration.乙酰胆碱酯酶抑制剂[14C]SDZ ENA 713在小型猪经口、静脉和皮肤给药后的吸收、代谢及处置情况。
Pharm Res. 1998 Oct;15(10):1614-20. doi: 10.1023/a:1011919603822.
2
Tetrahydroaminoacridine and Alzheimer's disease.四氢氨基吖啶与阿尔茨海默病
BMJ. 1994 Apr 2;308(6933):868-9. doi: 10.1136/bmj.308.6933.868.
3
Tetrahydroaminoacridine in Alzheimer's disease.四氢氨基吖啶与阿尔茨海默病
BMJ. 1989 Jun 10;298(6687):1579. doi: 10.1136/bmj.298.6687.1579-a.
4
Tetrahydroaminoacridine in Alzheimer's disease.四氢氨基吖啶与阿尔茨海默病
BMJ. 1989 May 6;298(6682):1250-1. doi: 10.1136/bmj.298.6682.1250-d.
5
Are drugs targeted at Alzheimer's disease useful? 2. Insufficient evidence of worthwhile benefit.治疗阿尔茨海默病的药物有用吗？2. 缺乏有价值益处的充分证据。
BMJ. 1990 Apr 28;300(6732):1132-3; discussion 1131. doi: 10.1136/bmj.300.6732.1132.
6
Activating the damaged basal forebrain cholinergic system: tonic stimulation versus signal amplification.激活受损的基底前脑胆碱能系统：持续性刺激与信号放大
Psychopharmacology (Berl). 1990;101(1):1-17. doi: 10.1007/BF02253710.
7
Behavioral screening for cognition enhancers: from indiscriminate to valid testing: Part I.认知增强剂的行为筛选：从无差别测试到有效测试：第一部分。
Psychopharmacology (Berl). 1992;107(2-3):144-59. doi: 10.1007/BF02245132.

本文引用的文献

1
Cholinomimetic treatment fails to improve memory disorders.拟胆碱治疗无法改善记忆障碍。
N Engl J Med. 1980 Sep 4;303(10):585-6. doi: 10.1056/nejm198009043031019.
2
Use of THA in treatment of Alzheimer-like dementia: pilot study in twelve patients.全髋关节置换术用于治疗阿尔茨海默病样痴呆：12例患者的初步研究
Biol Psychiatry. 1981 Feb;16(2):145-53.
3
Alzheimer's disease. Correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities.阿尔茨海默病。皮质胆碱乙酰转移酶活性与痴呆严重程度及组织学异常的相关性。
J Neurol Sci. 1982 Dec;57(2-3):407-17. doi: 10.1016/0022-510x(82)90045-4.
4
A post-mortem study of the cholinergic and GABA systems in senile dementia.老年痴呆症中胆碱能和γ-氨基丁酸系统的尸检研究。
Brain. 1982 Jun;105(Pt 2):313-30. doi: 10.1093/brain/105.2.313.
5
Modest facilitation on memory in dementia with combined lecithin and anticholinerestase treatment.卵磷脂与抗胆碱酯酶联合治疗对痴呆患者记忆有适度促进作用。
Biol Psychiatry. 1982 Feb;17(2):275-80.
6
Neurochemical characteristics of early and late onset types of Alzheimer's disease.早发型和晚发型阿尔茨海默病的神经化学特征
Br Med J (Clin Res Ed). 1984 Mar 31;288(6422):961-4. doi: 10.1136/bmj.288.6422.961.
7
The aminopyridines.氨基吡啶类
Gen Pharmacol. 1982;13(4):259-85. doi: 10.1016/0306-3623(82)90046-5.
8
Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementa.阿尔茨海默病和阿尔茨海默型老年痴呆症患者大脑皮质中生长抑素样免疫反应性降低。
Nature. 1980 Nov 20;288(5788):279-80. doi: 10.1038/288279a0.
9
A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease.一项关于高剂量卵磷脂治疗阿尔茨海默病的双盲、安慰剂对照试验。
J Neurol Neurosurg Psychiatry. 1985 Aug;48(8):736-42. doi: 10.1136/jnnp.48.8.736.
10
Oral physostigmine treatment of patients with Alzheimer's disease.口服毒扁豆碱治疗阿尔茨海默病患者。
Am J Psychiatry. 1985 Jan;142(1):28-33. doi: 10.1176/ajp.142.1.28.

Tetrahydroaminoacridine (THA) in Alzheimer's disease.

作者信息

Byrne J, Arie T

机构信息

Department of Health Care of the Elderly, Queen's Medical Centre, Nottingham.

出版信息

BMJ. 1989 Apr 1;298(6677):845-6. doi: 10.1136/bmj.298.6677.845.

DOI:10.1136/bmj.298.6677.845
PMID:2497817
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1836130/
Abstract
摘要