Alayli Gamze, Durmus Dilek, Ozkaya Ozan, Sen Halil Erdinc, Nalcacioglu Hulya, Bilgici Ayhan, Kuru Omer
Medical Faculty, Department of Physical Medicine and Rehabilitation (Drs Alayli, Durmus, Sen, Bilgici, and Kuru), Ondokuz Mayıs University, Samsun, Turkey; Medical Faculty, Department of Pediatric Nephrology (Drs Ozkaya and Nalcacioglu), Ondokuz Mayıs University, Samsun, Turkey.
Pediatr Phys Ther. 2014 Fall;26(3):347-52. doi: 10.1097/PEP.0000000000000052.
To examine functional capacity and muscle strength in children and youth with familial Mediterranean fever (FMF) as compared with controls, and to assess whether these factors influence quality of life (QOL) in FMF.
A total of 100 subjects with FMF and 55 control subjects (8-18 years old) without known health issues were enrolled in the study. The 6-Minute Walk Test (6MWT) was used to evaluate functional capacity. Quadriceps strength was measured with a hand-held dynamometer. Quality of life was evaluated with the Pediatric Quality of Life Inventory 4.0 (PedsQL 4.0).
Significant differences were found between subjects with FMF and controls in the 6MWT and strength test. PedsQL scores of subjects with FMF were significantly lower than the scores of the controls. The 6MWT and quadriceps strength were weakly correlated with the PedsQL.
Subjects with FMF displayed lower functional capacity and QOL than peers who are healthy. Decreased functional capacity was correlated with decreased QOL in those with FMF.
与对照组相比，研究家族性地中海热（FMF）患儿及青少年的功能能力和肌肉力量，并评估这些因素是否影响FMF患者的生活质量（QOL）。
本研究共纳入100例FMF患者和55例无已知健康问题的对照受试者（8至18岁）。采用6分钟步行试验（6MWT）评估功能能力。用手持测力计测量股四头肌力量。用儿童生活质量量表4.0（PedsQL 4.0）评估生活质量。
FMF患者与对照组在6MWT和力量测试中存在显著差异。FMF患者的PedsQL评分显著低于对照组。6MWT和股四头肌力量与PedsQL呈弱相关。
与健康同龄人相比，FMF患者的功能能力和生活质量较低。FMF患者功能能力下降与生活质量降低相关。
