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来自数码鼠尾草根部的两种二萜类化合物和一种环戊并[c]吡啶衍生物。

Two diterpenoids and a cyclopenta[c]pyridine derivative from roots of Salvia digitaloids.

作者信息

Wu Shwu-Jen, Huang Chieh-Hung, Chan Yu-Yi, Liao Yu-Ren, Hwang Tsong-Long, Wu Tian-Shung

机构信息

Department of Medical Laboratory Science and Biotechnology, Chung Hwa University of Medical Technology, Tainan 717, Taiwan.

Department of Chemistry, National Cheng Kung University, Tainan 701, Taiwan.

出版信息

Int J Mol Sci. 2014 Jun 27;15(7):11566-77. doi: 10.3390/ijms150711566.

DOI:10.3390/ijms150711566
PMID:24979137
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4139800/
Abstract

Two new glucosides, salviadigitoside A (1) and salviatalin A-19-O-β-glucoside (2), belonging to the salviatalin type diterpenoids, and a new cyclopenta[c]pyridine, salviadiginine A (3), were isolated from the roots of Salvia digitaloids. Structures of these compounds were determined on the basis of spectroscopic analysis. In addition, compounds 1-3 were evaluated for their anti-inflammatory activity, but the results showed a weak anti-inflammatory activity.

摘要

从数码鼠尾草的根部分离出两种新的糖苷,即鼠尾草洋地黄苷A(1)和鼠尾草他林A - 19 - O-β - 葡萄糖苷(2),它们属于鼠尾草他林型二萜类化合物,以及一种新的环戊并[c]吡啶,鼠尾草洋地黄宁A(3)。这些化合物的结构通过光谱分析确定。此外,对化合物1 - 3的抗炎活性进行了评估,但结果显示其抗炎活性较弱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97c7/4139800/11a63ae73e0a/ijms-15-11566-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97c7/4139800/dbbc478669e8/ijms-15-11566-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97c7/4139800/72dbfc5e8338/ijms-15-11566-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97c7/4139800/1fcdd6b9132d/ijms-15-11566-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97c7/4139800/11a63ae73e0a/ijms-15-11566-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97c7/4139800/dbbc478669e8/ijms-15-11566-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97c7/4139800/72dbfc5e8338/ijms-15-11566-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97c7/4139800/1fcdd6b9132d/ijms-15-11566-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97c7/4139800/11a63ae73e0a/ijms-15-11566-g004.jpg

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