Catassi Carlo, Gatti Simona, Fasano Alessio
*Department of Pediatrics, Università Politecnica delle Marche, 60121, Ancona, Italy †Center for Celiac Research, Massachustetts General Hospital for Children and Celiac Program at Harvard Medical School, Boston, MA.
J Pediatr Gastroenterol Nutr. 2014 Jul;59 Suppl 1:S7-9. doi: 10.1097/01.mpg.0000450393.23156.59.
The prevalence of celiac disease (CD) varies greatly, but several reports have shown that CD is increasing in frequency in different geographic areas. The increase in prevalence can be partially attributed to the improvement in diagnostic techniques and disease awareness; however the equally well documented rise in incidence in the last 30-40 years cannot be so easily explained. The new epidemiology of CD is now characterized by an increase of new cases in the historical CD areas (northern Europe and the United States) and more interestingly in a spread of the disease in new regions (Asian countries). A significant change in diet habits, particularly in gluten consumption as well as in infant feeding patterns are probably the main factors that can account for these new trends in CD epidemiology.
乳糜泻（CD）的患病率差异很大，但多项报告显示，在不同地理区域，CD的发病率正在上升。患病率的增加部分可归因于诊断技术的改进和疾病认知度的提高；然而，过去30至40年中同样有充分记录的发病率上升却无法如此轻易地得到解释。CD的新流行病学特征是，在历史上的CD高发地区（北欧和美国）新病例增加，更有趣的是，该病在新的地区（亚洲国家）也在蔓延。饮食习惯的显著变化，特别是麸质摄入量以及婴儿喂养方式的变化，可能是导致CD流行病学出现这些新趋势的主要因素。
