Waduthantri Samanthila, Tan Chien Hua, Fong Yee Wei, Tong Louis
Singapore Eye Research Institute , Singapore .
Curr Eye Res. 2015 May;40(5):490-5. doi: 10.3109/02713683.2014.932389. Epub 2014 Jun 30.
To evaluate the suitablity of commercially available moisture retention eyewear for treating evaporative dry eye.
Eleven patients with evaporative dry eyes were prescibed moisture retention eyewear for 3 months in addition to regular lubricant eye drops. Frequency and severity of dry eye symptoms, corneal fluorescein staining and tear break up time (TBUT) were evaluated at baseline and 3-month post-treatment. Main outcome measure was global symptom score (based on severity and frequency of dry eye symptoms on a visual analog scale) and secondary outcomes were changes in sectoral corneal fluorescein staining and tear break up time (TBUT) from pre-treatment level.
There was a significant improvement in dry eye symptoms after using moisture retention eyewear for 3 months (p < 0.05). Corneal fluorescein staining in all five zones of the cornea in both eyes improved significantly (p < 0.05). There was no significant improvement in TBUT. Patients used ocular lubricants less frequently (p < 0.05) compared to the commencement of the study. Patients found moisture retention eyewear to be useful in relieving dry eye symptoms in windy, air-conditioned environments or when doing vision-related daily tasks.
This study shows that moisture retention eyewear might be a valuable adjunct in management of evaporative dry eye and this new design of commercially available eyewear could have a good acceptability rate.
评估市售保湿眼镜治疗蒸发型干眼的适用性。
11例蒸发型干眼患者除使用常规润滑眼药水外，还佩戴保湿眼镜3个月。在基线和治疗后3个月评估干眼症状的频率和严重程度、角膜荧光素染色及泪膜破裂时间（TBUT）。主要观察指标为整体症状评分（基于视觉模拟量表上干眼症状的严重程度和频率），次要观察指标为角膜各象限荧光素染色及泪膜破裂时间（TBUT）相对于治疗前水平的变化。
佩戴保湿眼镜3个月后，干眼症状有显著改善（p < 0.05）。双眼角膜五个区域的荧光素染色均有显著改善（p < 0.05）。泪膜破裂时间无显著改善。与研究开始时相比，患者使用眼部润滑剂的频率降低（p < 0.05）。患者发现保湿眼镜在有风的环境、空调环境或进行与视力相关的日常任务时，有助于缓解干眼症状。
本研究表明，保湿眼镜可能是治疗蒸发型干眼的一种有价值的辅助手段，这种新设计的市售眼镜可能具有较高的接受率。
