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干眼病和睑板腺功能障碍的评估与管理:提供新加坡框架。

Assessment and Management of Dry Eye Disease and Meibomian Gland Dysfunction: Providing a Singapore Framework.

机构信息

Corneal and External Eye Disease Service, Singapore National Eye Centre, Singapore.

Eye Academic Clinical Program, Duke-National University of Singapore, Singapore.

出版信息

Asia Pac J Ophthalmol (Phila). 2021 Nov 11;10(6):530-541. doi: 10.1097/APO.0000000000000417.

Abstract

The purpose of this article is to provide a framework for general ophthalmologists in Singapore to manage dry eye. This framework considers the evidence in the literature as well as recommendations from expert panels such as the Tear Film & Ocular Surface Society Dry Eye Workshop II and the Asia Cornea Society Workgroup.This article covers the assessment of patient medical history and ask triage questions to identify local and systemic causes of dry eye disease (DED), excluding other possible causes, as well as the risk factors for DED and ocular surface inflammation. Evaluation of clinical signs to establish the diagnosis of DED and differentiation from other causes of irritable, red eyes are described. Tests for understanding the underlying disease processes and severity of DED are also presented.Management of dry eye should involve patient education and engagement. Information about the natural history and chronic nature of DED should be provided to improve long-term management of the disease and enhance compliance. Aggravating factors should be removed or lessened.We provide a guide to determine the most appropriate treatment (or combination of treatments) based on the severity and cause(s) of the disease, as well as the patient's needs and preferences. The aim of the management is to relieve ocular discomfort and prevent worsening of symptoms and signs, as well as to optimize visual function and minimize structural ocular damage. We also discuss the systematic follow-up and assessment of treatment response, as well as monitoring side effects of treatment, bearing in mind continuous support and reassurance to patients.

摘要

本文旨在为新加坡的普通眼科医生提供一种管理干眼的框架。该框架考虑了文献中的证据以及泪膜和眼表面学会干眼工作坊 II 和亚洲角膜学会工作组等专家小组的建议。本文涵盖了评估患者病史和询问分诊问题以确定干眼疾病 (DED) 的局部和全身原因,排除其他可能的原因,以及 DED 和眼表面炎症的危险因素。描述了评估临床体征以建立 DED 诊断并与其他引起眼刺激和眼红的原因区分开来的方法。还介绍了用于了解潜在疾病过程和 DED 严重程度的测试。干眼的管理应包括患者教育和参与。应提供有关 DED 的自然病史和慢性性质的信息,以改善疾病的长期管理并提高依从性。应消除或减轻加重因素。我们提供了一个指南,根据疾病的严重程度和原因以及患者的需求和偏好,确定最合适的治疗方法(或联合治疗方法)。管理的目的是缓解眼部不适,防止症状和体征恶化,以及优化视觉功能并最小化结构眼损伤。我们还讨论了系统的随访和治疗反应评估,以及监测治疗的副作用,同时牢记为患者提供持续的支持和安慰。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbdd/8673856/c71bf2230c37/ap9-10-530-g001.jpg

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