Sakurai Yasuyoshi, Uchida Michiko, Mimura Fumiaki
Masui. 2014 Jun;63(6):636-9.
To test safety and efficacy of ORT (oral rehydration therapy), we compared an ORT group with an intravenous infusion (i.v.) group by gastric fluid (volume and pH) obtained by endoscope and gastric ultrasonography examination.
Twenty six patients scheduled for endoscopic surgery were assigned to an ORT group or an i.v. group by standardized clinical path. After gastric ultrasonography examinations to calculate CSA (cross sectional area) of gastric antrum, general anesthesia was induced. Immediately after anesthesia induction, gastric fluid was obtained by endoscopy, and its volume and pH were measured.
Fifteen and eleven patients were assigned to ORT group and iv group, respectively. In ORT group, CSA was median 1.9 cm2 (95% CI:1.8-2.6 cm2), gastric volume was median 11 ml (95% CI: 8-18 ml) and pH was median 3.6 (range: 1.2-8.8), and in i.v. group CSA was median 1.8 cm2 (95% CI: 1.6-2.7 cm2), gastric volume was median 4 ml (95% CI: 3-12 ml), and pH was median 3.1 (range: 1.2-7.2). There was no significance between the two groups.
Gastric volume in ORS group was not smaller compared with that in i.v. group, and there was no significant difference in pH between the groups.
为测试口服补液疗法(ORT)的安全性和有效性,我们通过内窥镜检查和胃超声检查获取胃液(容量和pH值),将ORT组与静脉输液(i.v.)组进行了比较。
26例计划接受内窥镜手术的患者按标准化临床路径被分配到ORT组或i.v.组。在进行胃超声检查以计算胃窦横截面积(CSA)后,诱导全身麻醉。麻醉诱导后立即通过内窥镜检查获取胃液,并测量其容量和pH值。
ORT组和i.v.组分别有15例和11例患者。ORT组中,CSA中位数为1.9平方厘米(95%可信区间:1.8 - 2.6平方厘米),胃容量中位数为11毫升(95%可信区间:8 - 18毫升),pH值中位数为3.6(范围:1.2 - 8.8);i.v.组中,CSA中位数为1.8平方厘米(95%可信区间:1.6 - 2.7平方厘米),胃容量中位数为4毫升(95%可信区间:3 - 12毫升),pH值中位数为3.1(范围:1.2 - 7.2)。两组之间无显著差异。
口服补液盐(ORS)组的胃容量与i.v.组相比并不小,且两组之间的pH值无显著差异。