Bouzoubaa S, Khazana M, Slimani F, Chekkoury E I, Benyahya I
Odontostomatol Trop. 2014 Mar;37(145):40-6.
Metastatic tumors result from hematogenous spread through a tumor located at a distance. All these tumors represent about 1% of malignant tumors of the oral cavity (1). The most common location is the mandible (70%), more rarely maxillary (2). The most frequently encountered tumors are carcinomas or adenocarcinomas of mammary origin, brocho-lung, prostate, kidney or another. This study reports the case of a 46 year-old man, who presented for consultation with a low left laterofacial swelling, paresthesia lip and chin straight associated with pain at the lower edge of the mandible evolving for 2 months. The patient is known to take alcohol and tobacco for 20 years. The panoramic radiograph showed radiolucent image with blurred boundaries at the lower right premolar region. Dentascan revealed an irregular osteolytic lesion with rupture of the table lingual. After surgical exploration, the pathological examination is for a well-differentiated and invasive adenocarcinoma of the mandible. Extension work-up shows the presence of a tumor right lung, a lytic lesion at the 8th costal arch, the fourth dorsal vertebra and another location in fibula. The surgical exploration of pulmonary was performed and confirmed the pulmonary primitive localization of adenocarcinoma.
转移性肿瘤是由远处的肿瘤通过血行播散引起的。所有这些肿瘤约占口腔恶性肿瘤的1%（1）。最常见的部位是下颌骨（70%），上颌骨较少见（2）。最常遇到的肿瘤是乳腺来源、支气管-肺、前列腺、肾脏或其他部位的癌或腺癌。本研究报告了一例46岁男性患者，因左侧面下部肿胀、唇部和下巴麻木伴下颌下缘疼痛2个月前来咨询。已知该患者有20年饮酒和吸烟史。全景片显示右下前磨牙区有边界模糊的透射影像。牙科扫描显示有不规则的溶骨性病变，舌侧骨板破裂。手术探查后，病理检查为下颌骨高分化浸润性腺癌。进一步检查显示右肺有肿瘤，第8肋弓、第4胸椎有溶骨性病变，腓骨还有另一处病变。对肺部进行了手术探查，证实腺癌的原发部位在肺部。
