Alexeyenko Andrey, Lindberg Julia, Pérez-Bercoff Asa, Sonnhammer Erik L L
Stockholm Bioinformatics Center, Albanova, Stockholm University, SE-106 91, Stockholm, Sweden.
Stockholm Bioinformatics Center, Albanova, Stockholm University, SE-106 91, Stockholm, Sweden.
Drug Discov Today Technol. 2006 Summer;3(2):137-43. doi: 10.1016/j.ddtec.2006.06.002.
Orthologs are an indispensable bridge to transfer biological knowledge between species, from protein annotations to sophisticated disease models. However, orthology assignment is not trivial. A large number of resources now exist, each with its own idiosyncrasies. The goal of this review is to compare their contents and clarify which database is most suited for a certain task.:
直系同源基因是在物种间传递生物学知识的不可或缺的桥梁，从蛋白质注释到复杂的疾病模型。然而，直系同源基因的分配并非易事。现在有大量的资源，每个资源都有其自身的特点。本综述的目的是比较它们的内容，并阐明哪个数据库最适合某项任务。
