Department of Neurological Surgery, University of California, San Francisco, California;
J Neurosurg Spine. 2014 Jul;21(1):31-6. doi: 10.3171/2014.4.SPINE14268.
In an effort to diminish pain or progressive instability, due to either the pathological process or as a result of surgical decompression, one of the primary goals of a fusion procedure is to achieve a solid arthrodesis. Assuming that pain and disability result from lost mechanical integrity of the spine, the objective of a fusion across an unstable segment is to eliminate pathological motion and improve clinical outcome. However, conclusive evidence of this correlation, between successful fusion and clinical outcome, remains elusive, and thus the necessity of documenting successful arthrodesis through radiographic analysis remains debatable. Although a definitive cause and effect relationship has not been demonstrated, there is moderate evidence that demonstrates a positive association between radiographic presence of fusion and improved clinical outcome. Due to this growing body of literature, it is recommended that strategies intended to enhance the potential for radiographic fusion are considered when performing a lumbar arthrodesis for degenerative spine disease.
为了减轻疼痛或因病理过程或手术减压而导致的渐进性不稳定,融合手术的主要目标之一是实现牢固的关节融合。假设疼痛和残疾是由于脊柱机械完整性丧失引起的,那么在不稳定节段进行融合的目的是消除病理性运动并改善临床结果。然而,成功融合与临床结果之间存在相关性的确切证据仍然难以捉摸,因此通过放射学分析来证明关节融合成功的必要性仍然存在争议。尽管尚未证明明确的因果关系,但有中等证据表明融合的放射学表现与临床结果的改善之间存在正相关。由于这方面文献的不断增加,建议在因退行性脊柱疾病而行腰椎融合术时,考虑采用旨在增强放射学融合可能性的策略。