Department of Neurosurgery, University of Wisconsin, Madison, Wisconsin;
J Neurosurg Spine. 2014 Jul;21(1):62-6. doi: 10.3171/2014.4.SPINE14275.
Lumbar stenosis is one of the more common radiographic manifestations of the aging process, leading to narrowing of the spinal canal and foramen. When stenosis is clinically relevant, patients often describe activity-related low-back or lower-extremity pain, known as neurogenic claudication. For those patients who do not improve with conservative care, surgery is considered an appropriate treatment alternative. The primary objective of surgery is to reconstitute the spinal canal. The role of fusion, in the absence of a degenerative deformity, is uncertain. The previous guideline recommended against the inclusion of lumbar fusion in the absence of spinal instability or a likelihood of iatrogenic instability. Since the publication of the original guidelines, numerous studies have demonstrated the role of surgical decompression in this patient population; however, few have investigated the utility of fusion in patients without underlying instability. The majority of studies contain a heterogeneous cohort of subjects, often combining patients with and without spondylolisthesis who received various surgical interventions, limiting fusions to those patients with instability. It is difficult if not impossible, therefore, to formulate valid conclusions regarding the utility of fusion for patients with uncomplicated stenosis. Lower-level evidence exists, however, that does not demonstrate an added benefit of fusion for these patients; therefore, in the absence of deformity or instability, the inclusion of a fusion is not recommended.
腰椎狭窄症是衰老过程中较为常见的影像学表现之一,导致椎管和神经孔狭窄。当狭窄与临床相关时,患者常描述与活动相关的下腰痛或下肢疼痛,称为神经性跛行。对于那些保守治疗后无改善的患者,手术被认为是一种合适的治疗选择。手术的主要目标是重建椎管。在没有退行性畸形的情况下,融合的作用尚不确定。先前的指南建议在没有脊柱不稳定或医源性不稳定的可能性的情况下,不包括腰椎融合。自原始指南发布以来,许多研究已经证明了手术减压在这一患者群体中的作用;然而,很少有研究调查融合在没有潜在不稳定的患者中的效用。大多数研究包含了一个异质的受试者队列,通常将接受各种手术干预的合并有和没有脊椎滑脱的患者结合在一起,将融合限制在不稳定的患者中。因此,很难(如果不是不可能的话)对单纯狭窄患者融合的效用得出有效的结论。然而,存在较低水平的证据表明融合对这些患者没有额外的益处;因此,在没有畸形或不稳定的情况下,不建议进行融合。